CLUSTAL W(1.81) multiple sequence alignment XP_004857018.1/1-875 MDRAVLR-AAMGEKKEGGGGGAAAAADGASGAAAGRALQQCGQLQKLIDISIGSLRGLRT ENSCPOP00000000837/1-859 ------------------------------------------------------------ ENSP00000323178/1-923 MDRAALRAAAMGEKKEGGGGGDAAAAEGGAGAAASRALQQCGQLQKLIDISIGSLRGLRT ENSMUSP00000018478/1-873 MDRAALRAAAMGEKKEGGGGG--AAADGGAGAAVSRALQQCGQLQKLIDISIGSLRGLRT ENSRNOP00000049882/1-520 ------------------------------------------------------------ XP_004857018.1/1-875 KCAVSNDLTQQEIRTLEARLVRYICKQRQCKLSVAPGDRTPELNSYPRFSDWLDTFNVRP ENSCPOP00000000837/1-859 ----------------QARLVRYICKQRQCKLSVAPSDRTPELNSYPRFRDWLDTFNVRP ENSP00000323178/1-923 KCAVSNDLTQQEIRTLEAKLVRYICKQRQCKLSVAPGERTPELNSYPRFSDWLYTFNVRP ENSMUSP00000018478/1-873 KCSVSNDLTQQEIRTLEAKLVKYICKQQQSKLSVTPSDRTAELNSYPRFSDWLYIFNVRP ENSRNOP00000049882/1-520 ------------------------------------------------------------ XP_004857018.1/1-875 EVTQVLPAQLT---LDALLEMDEAKVKETLQRCGASAEECGRLQQALTCLRKVTGLGGEH ENSCPOP00000000837/1-859 AVAQEILRELTGDQLDALLEMDEAKVKETLQRCGASTEECGRLQQALTCLRKVTGLGGEH ENSP00000323178/1-923 EVVQEIPRDLT---LDALLEMNEAKVKETLRRCGASGDECGRLQYALTCLRKVTGLGGEH ENSMUSP00000018478/1-873 EVVQEIPQELT---LDALLEMDEAKAKEMLRRWGASTEECSRLQQALTCLRKVTGLGGEH ENSRNOP00000049882/1-520 ------------------------------------------------------------ XP_004857018.1/1-875 KEDSGWSSSDARRESSSGPSVDTLSPASLAWPPGSSLLGRVGGGAQGPRSVSVSALPASD ENSCPOP00000000837/1-859 KEDSGWSSSEARRESSSGPSVDTLSPATLPWPPGSSLLGRVGSGAQGLRSVSVSALPASD ENSP00000323178/1-923 KEDSSWSSLDARRESGSGPSTDTLSAASLPWPPGSSQLGRAGNSAQGPRSISVSALPASD ENSMUSP00000018478/1-873 KMDSGWSSTDA-RDSSLGPPMDMLSS-----------LGRAGASTQGPRSISVSALPASD ENSRNOP00000049882/1-520 ------------------------------------------------------------ XP_004857018.1/1-875 SPAPGLSEGFSDTCIPLHTSGRLTPRALHSFITPPATPQLRRHAKLKPPRTPPPPSRKVF ENSCPOP00000000837/1-859 SPAPGLSEGLSDTCIPLHASGRLTPRALHSFITPPATPQLRRHAKLKPPRTPPPPSRKVF ENSP00000323178/1-923 SPTPSFSEGLSDTCIPLHASGRLTPRALHSFITPPTTPQLRRHTKLKPPRTPPPPSRKVF ENSMUSP00000018478/1-873 SPVPGLSEGLSDSCIPLHTSGRLTPRALHSFITPPTTPQLRRHAKLKPPRTPPPPSRKVF ENSRNOP00000049882/1-520 ------------------------------------------------------------ XP_004857018.1/1-875 QLLPSFPTLTRSKSHESQLGNRIDEVSSMRFDLSRGSPQMVRRDIGLSVTHRFSTKSWLS ENSCPOP00000000837/1-859 QLLPSFPTLTRSKSHESQLGNRIDEVSSMKFDLSHGSPQMVRRDIGLSVTHRFSTKSWLS ENSP00000323178/1-923 QLLPSFPTLTRSKSHESQLGNRIDDVSSMRFDLSHGSPQMVRRDIGLSVTHRFSTKSWLS ENSMUSP00000018478/1-873 QLLPSFPTLTRSKSHESQLGNRIDDVTPMKFELPHGSPQLVRRDIGLSVTHRFSTKSWLS ENSRNOP00000049882/1-520 ------------------------------------------------------------ XP_004857018.1/1-875 QVCHVCQKSMMFGVKCKHCRLKCHNKCTKEAPACRISFLPITRLRRTESVPSDINNPVDR ENSCPOP00000000837/1-859 QVCHVCQKSMMFGVKCKHCRLKCHNKCTKEAPACRISFLPLTRLRRTESVPSDINNPVDR ENSP00000323178/1-923 QVCHVCQKSMIFGVKCKHCRLKCHNKCTKEAPACRISFLPLTRLRRTESVPSDINNPVDR ENSMUSP00000018478/1-873 QVCNVCQKSMIFGVKCKHCRLKCHNKCTKEAPACRITFLPLARLRRTESVPSDINNPVDR ENSRNOP00000049882/1-520 ---------MMFGVKCKHCRLKCHNKCTKEAPACRISFLPLARLRRTESVPSDINNPVDR *:*************************:***::****************** XP_004857018.1/1-875 AAEPHFGTLPKALTKKEHPPVMNHLDSSSNPSSTTSSTPSSPAPFPASSHPSSATTPPNP ENSCPOP00000000837/1-859 AAEPHFGTLPKALTKKEHPPAVNHLDSSSNPSSTTSSTPSSPAPFPTSSNPSSATTPPNP ENSP00000323178/1-923 AAEPHFGTLPKALTKKEHPPAMNHLDSSSNPSSTTSSTPSSPAPFPTSSNPSSATTPPNP ENSMUSP00000018478/1-873 AAEPHFGTLPKALTKKEHPPAMN-LDSSSNPSSTTSSTPSSPAPFLTSSNPSSATTPPNP ENSRNOP00000049882/1-520 AAEPHFGTLPKALTKKEHPPAMN-LDSSSNPSSTTSSTPSSPAPFLTSSNPSSATTPPNP ********************.:* ********************* :**:********** XP_004857018.1/1-875 SPGQRDSRFSFPAAYFIHHRQQFIFP-------------------------------DIS ENSCPOP00000000837/1-859 SPGQRDSRFNFPAAYFIHHRQQFIFPAPLPSGGRTWELLVLMPFRGSFGETGRERATDIS ENSP00000323178/1-923 SPGQRDSRFNFPAAYFIHHRQQFIFP--VPSAGHCWKCLLI-------AESLKENAFNIS ENSMUSP00000018478/1-873 SPGQRDSRFSFP---------------------------------------------DIS ENSRNOP00000049882/1-520 SPGQRDSRFNFP---------------------------------------------DIS *********.** :** XP_004857018.1/1-875 AFPQAAPLPDGADNTRLDDQPKAEVLEAHEVEAEEPEAGKSEAEDD-EDEVDDLPSSRRP ENSCPOP00000000837/1-859 AFPQAAPHPEAAENTRPDEQQKAEVMEAQQAEAEEPEAGKSEAEDD-EDEVDDLPSSRWP ENSP00000323178/1-923 AFAHAAPLPEAADGTRLDDQPKADVLEAHEAEAEEPEAGKSEAEDD-EDEVDDLPSSRRP ENSMUSP00000018478/1-873 ACSQAAPLSSTADSTRLDDQPKTDVLGVHEAEAEEPEAGKSEAEDDEEDEVDDLPSSRRP ENSRNOP00000049882/1-520 ACPQAAPLSSTADSTRLDDQPKTDVLGVPEAEAEEPEAGKSEAEDD-EDEIDDLPSSRRH * .:*** .. *:.** *:* *::*: . :.*************** ***:******* XP_004857018.1/1-875 WRGPISRKTSQTSVYLQEWDIPFEQVELGELIGQGRWGRVHRGRWHGEVAIRLLEMDGHN ENSCPOP00000000837/1-859 WRGPISRKASQTSVYLQEWDIPFEQVELGELIGQGRWGRVHRGRWHGEVAIRLLEMDGHN ENSP00000323178/1-923 WRGPISRKASQTSVYLQEWDIPFEQVELGEPIGQGRWGRVHRGRWHGEVAIRLLEMDGHN ENSMUSP00000018478/1-873 WRGPISRKASQTSVYLQEWDIPFEQVELGEPIGQGRWGRVHRGRWHGEVAIRLLEMDGHN ENSRNOP00000049882/1-520 WRGPISRKASQTSVYLQEWDIPFEQVELGEPIGQGRWGRVHRGRWHGEVAIRLLEMDGHN ********:********************* ***************************** XP_004857018.1/1-875 QDHLKLFKKEVMNYRQTRHENVVLFMGACMNPPHLAIITSFCKGRTLHSFVRDPKTSLDI ENSCPOP00000000837/1-859 QDHLKLFKKEVMNYRQTRHENVVLFMGACMNPPHLAIITSFCKGRTLHSFVRDPKTSLDI ENSP00000323178/1-923 QDHLKLFKKEVMNYRQTRHENVVLFMGACMNPPHLAIITSFCKGRTLHSFVRDPKTSLDI ENSMUSP00000018478/1-873 QDHLKLFKKEVMNYRQTRHENVVLFMGACMNPPHLAIITSFCKGRTLHSFVRDPKTSLDI ENSRNOP00000049882/1-520 QDHLKLFKKEVMNYRQTRHENVVLFMGACMNPPHLAIITSFCKGRTLHSFVRDPKTSLDI ************************************************************ XP_004857018.1/1-875 NKTRQIAQEIIKGMGYLHAKGIVHKDLKSKNVFYDNGKVVITDFGLFGISGVVREERREN ENSCPOP00000000837/1-859 NKTRQIAQEIIKGMGYLHAKGIVHKDLKSKNVFYDNGKVVITDFGLFGISGVVREERREN ENSP00000323178/1-923 NKTRQIAQEIIKGMGYLHAKGIVHKDLKSKNVFYDNGKVVITDFGLFGISGVVREGRREN ENSMUSP00000018478/1-873 NKTRQIAQEIIKGMGYLHAKGIVHKDLKSKNVFYDNGKVVITDFGLFGISGVVREERREN ENSRNOP00000049882/1-520 NKTRQIAQEIIKGMGYLHAKGIVHKDLKSKNVFYDNGKVVITDFGLFGISGVVREERREN ******************************************************* **** XP_004857018.1/1-875 QLKLSHDWLCYLAPEIVCEMTPGKDEDQLPFSKAADVYAFGTVWYELQARDWPFKHQPAE ENSCPOP00000000837/1-859 QLKLSHDWLCYLAPEIVREMTPGKDEDQLPFSKAADVYAFGTVWYELQARDWPFKHQPAE ENSP00000323178/1-923 QLKLSHDWLCYLAPEIVREMTPGKDEDQLPFSKAADVYAFGTVWYELQARDWPLKNQAAE ENSMUSP00000018478/1-873 QLKLSHDWLCYLAPEIVREMIPGRDEDQLPFSKAADVYAFGTVWYELQARDWPFKHQPAE ENSRNOP00000049882/1-520 QLKLSHDWLCYLAPEIVREMIPGRDEDQLPFSKAADVYAFGTVWYELQARDWPFKHQPAE ***************** ** **:*****************************:*:*.** XP_004857018.1/1-875 ALIWQIGSGEGMKRVLGSVSLGKEVSEILSACWAFDLQERPSFSMLMDMLEKLPKLNRRL ENSCPOP00000000837/1-859 ALIWQIGSGEGMRRVLASVSLGKEVSEILSACWAFDLQERPSFSLLMDMLEKLPKLNRRL ENSP00000323178/1-923 ASIWQIGSGEGMKRVLTSVSLGKEVSEILSACWAFDLQERPSFSLLMDMLEKLPKLNRRL ENSMUSP00000018478/1-873 ALIWQIGSGEGVRRVLASVSLGKEVGEILSACWAFDLQERPSFSLLMDMLERLPKLNRRL ENSRNOP00000049882/1-520 ALIWQIGSGEGVKRVLASVSLGKEVGEILSACWAFDLQERPSFSLLMDMLEKLPKLNRRL * *********::*** ********.******************:******:******** XP_004857018.1/1-875 SHPGHFWKSAE------------------------- ENSCPOP00000000837/1-859 SHPGHFWKSADINSSKVVPRFERFGLGALESSNPKM ENSP00000323178/1-923 SHPGHFWKSADINSSKVVPRFERFGLGVLESSNPKM ENSMUSP00000018478/1-873 SHPGHFWKSADINSSKVMPRFERFGLGTLESGNPKM ENSRNOP00000049882/1-520 SHPGHFWKSADANSSKVMPRFERFGLGTLESSNPKM **********: