CLUSTAL W(1.81) multiple sequence alignment ENSMUSP00000119320/1-1129 ---QRRKLMSCGCAGEEKRVGTRTVFVGNHPISGTEPYIAQRFCDNRIVSSKYTLWNFLP ENSRNOP00000048676/1-1129 ---MLKLTLPRQCAGEEKRVGTRTVFVGNHPISGTEAYIAQRFCDNRIVSSKYTLWNFLP ENSP00000332756/1-1132 MQMVPSLPPASECAGEEKRVGTRTVFVGNHPVSETEAYIAQRFCDNRIVSSKYTLWNFLP XP_004862367.1/1-1063 ---MFRRSLNRFCAGEEKRVGTRTVFVGNHPISETETYIAQRFCDNRIVSSKYTLWNFLP ENSCPOP00000000785/1-1002 ------------CAGEEKRVGTRTVFVGNRPLSETETYVAQRFCDNRIVSSKYTLWNFLP *****************:*:* **.*:********************* ENSMUSP00000119320/1-1129 KNLFEQFRRIANFYFLIIFLVQVTVDTPTSPVTSGLPLFFVITVTAIKQGYEDWLRHRAD ENSRNOP00000048676/1-1129 KNLFEQFRRIANFYFLIIFLVQVTVDTPTSPVTSGLPLFFVITVTAIKQGYEDWLRHRAD ENSP00000332756/1-1132 KNLFEQFRRIANFYFLIIFLVQVTVDTPTSPVTSGLPLFFVITVTAIKQGYEDCLRHRAD XP_004862367.1/1-1063 KNLFEQFRRIANFYFLIIFLVQVTVDTPTSPVTSGLPLFFVITVTAIKQGYEDWLRHRAD ENSCPOP00000000785/1-1002 KNLFEQFRRIANFYFLIIFLVQVTVDTPTSPVTSGLPLFFVITVTAIKQGYEDWLRHRAD ***************************************************** ****** ENSMUSP00000119320/1-1129 NEVNKSAVYIIENAKRVRKESEKIKVGDVVEVQANETFPCDLILLSSCTTDGTCYVTTAS ENSRNOP00000048676/1-1129 NEVNKSTVYIIENAKRVRKESEKIKVGDVVEVQADETFPCDLILLSSCTTDGTCYVTTAS ENSP00000332756/1-1132 NEVNKSTVYIIENAKRVRKESEKIKVGDVVEVQADETFPCDLILLSSCTTDGTCYVTTAS XP_004862367.1/1-1063 NEVNKSTVYIIENAKRVRKESEKIKVGDVVEVQADETFPCDLILLSSCTTDGTCYVTTAS ENSCPOP00000000785/1-1002 NEVNKSTVYIIENAKRVKKESEKIKVGDVVEVQADETFPCDLILLSSCTTDGTCYVTTAS ******:**********:****************:************************* ENSMUSP00000119320/1-1129 LDGESNCKTHYAVRDTIALCTAESIDNLRATIECEQPQPDLYRFVGRISIYSNSIEAVAR ENSRNOP00000048676/1-1129 LDGESNCKTHYAVRDTIELCTAESIDNLRAAIECEQPQPDLYKFVGRISIYSNSIEAVAR ENSP00000332756/1-1132 LDGESNCKTHYAVRDTIALCTAESIDTLRAAIECEQPQPDLYKFVGRINIYSNSLEAVAR XP_004862367.1/1-1063 LDGESNCKTHYAVRDTIALCTAESIDRLRAAIECEQPQPDLYKFVGRINIYSNSLEAVAR ENSCPOP00000000785/1-1002 LDGESNCKTYYAVRDTIALCTAESIDSLRAAIECEQPQPDLYKFVGRINIYSNSLEAVAR *********:******* ******** ***:***********:*****.*****:***** ENSMUSP00000119320/1-1129 SLGPENLLLKGATLKNTKKIYGVAVYTGMETKMALNYQGKSQKCSAVEKSINAFLIVYLF ENSRNOP00000048676/1-1129 SLGPENLLLKGATLKNTKKIYGVAVYTGMETKMALNYQGKSQKRSAVEKSINAFLIVYLF ENSP00000332756/1-1132 SLGPENLLLKGATLKNTEKIYGVAVYTGMETKMALNYQGKSQKRSAVEKSINAFLIVYLF XP_004862367.1/1-1063 SLGPENLLLKGATLKNTKKIYGVAVYTGMETKMALNYQGKSQKRSAVEKSINAFLIVYLF ENSCPOP00000000785/1-1002 SLGPENLLLKGATLKNTKKIYGVAVYTGMETKMALNYQGKSQKRSAVEKSINAFLIVYLF *****************:************************* **************** ENSMUSP00000119320/1-1129 ILLTKAAVCTTLKYVWQSSPYNDEPWYNQKTQKERETFQVLKMFTDFLSFMVLFNFIIPV ENSRNOP00000048676/1-1129 ILLTKAAVCTTLKYVWQSTPYNDEPWYNQKTQKERETFKVLKMFTDFLSFMVLFNFIIPV ENSP00000332756/1-1132 ILLTKAAVCTTLKYVWQSTPYNDEPWYNQKTQKERETLKVLKMFTDFLSFMVLFNFIIPV XP_004862367.1/1-1063 ILLTKAAVCTTLKYIWQSTPHNDEPWYNRKTQKERETFK--------------------- ENSCPOP00000000785/1-1002 ILLTKAAVCTTLKYIWQSTPYNDEPWYNQKTQKERETFKVLKMFTDFLSFMVLFNFIIPV **************:***:*:*******:********:: ENSMUSP00000119320/1-1129 SMYVTVEMQKFLGSFFISWDKDFFDEEINEGALVNTSDLNEELGQVDYVFTDKTGTLTEN ENSRNOP00000048676/1-1129 SMYVTVEMQKFLGSFFISWDKDFFDEEINEGALVNTSDLNEELGQVDYVFTDKTGTLTEN ENSP00000332756/1-1132 SMYVTVEMQKFLGSFFISWDKDFYDEEINEGALVNTSDLNEELGQVDYVFTDKTGTLTEN XP_004862367.1/1-1063 ---------------------------------------------VDYVFTDKTGTLTEN ENSCPOP00000000785/1-1002 SMYVTVEMQKFLGSFFISWDKDFYDEEINEGALVNTSDLNEELGQVDYVFTDKTGTLTEN *************** ENSMUSP00000119320/1-1129 SMEFIECCIDGHKYKGTTQEVDGLSQTDGPLAYFDKADKNREALFLRALCLCHTVEMKTN ENSRNOP00000048676/1-1129 SMEFIECCIDGHKYKGTTQEVDGLSQIDGPLAYFDKADKNREELFLRALCLCHTVEIKTN ENSP00000332756/1-1132 SMEFIECCIDGHKYKGVTQEVDGLSQTDGTLTYFDKVDKNREELFLRALCLCHTVEIKTN XP_004862367.1/1-1063 SMEFIECSIDGHKYKDETQEVDGLSQTDGPLTYFDKADKDREELFLRALCLCHTVETKTN ENSCPOP00000000785/1-1002 SMEFIECCIDGHKYRSETQEVDGLSQTDGPLTFFDKADKNREELFLRALCLCHTVETKTN *******.******:. ********* **.*::***.**:** ************* *** ENSMUSP00000119320/1-1129 DDVDGPVEGAGFTYISSSPDEIALVKGAKRFGFTFLGNQNGYIRVENQRKEIEEYELLHT ENSRNOP00000048676/1-1129 DAVDGPIEGAQFTYISSSPDEIALVKGAQKFGFTFLGNWNGHIRVENQRKEIEEYELLHT ENSP00000332756/1-1132 DAVDGATESAELTYISSSPDEIALVKGAKRYGFTFLGNRNGYMRVENQRKEIEEYELLHT XP_004862367.1/1-1063 DAVDGATESAELTYVSSSPDEIALVKGAKKYGFTFLGNQNGLMRVENQRKEVEEYELLHT ENSCPOP00000000785/1-1002 DAVDGATEPAELTYVSSSPDEIALVKGAKKFGFTFLGNRNGLMRVENQRKEVEEYELLHT * ***. * * :**:*************:::******* ** :********:******** ENSMUSP00000119320/1-1129 LNFDSVRRRMSVIVRTQKGDILLFCKGADSSIFPRVHSHQIELTKDHVERNAMDGYRTLC ENSRNOP00000048676/1-1129 LNFDSVRRRMSVIVRTQGGDILLFCKGADSSIFPRVHSHEIDLTKVHVERNAMDGYRTLC ENSP00000332756/1-1132 LNFDAVRRRMSVIVKTQEGDILLFCKGADSAVFPRVQNHEIELTKVHVERNAMDGYRTLC XP_004862367.1/1-1063 LNFDAVRRRMSVIVKTQGGDILLFCKGADSAVFPRVQNHEIELTKAHVERNAMDGYRTLC ENSCPOP00000000785/1-1002 LNFDAVRRRMSVIVKTPGGDILLFCKGADSAVFPRVHNHEIELTKAHVERNAMDGYRTLC ****:*********:* ************::****:.*:*:*** ************** ENSMUSP00000119320/1-1129 VAFKEIPPDDFERINAQLVEAKMALQDREEKLEKVFDEIETNMNLIGATAVEDKLQDQAA ENSRNOP00000048676/1-1129 VAFKEIPPDDFERINVQLIEAKMALQDREEKLEKIFDVIETNMNLIGATAVEDKLQDQAA ENSP00000332756/1-1132 VAFKEIAPDDYERINRQLIEAKMALQDREEKMEKVFDDIETNMNLIGATAVEDKLQDQAA XP_004862367.1/1-1063 VAFKEIAPDDYERINRQLIEAKMALQDREEKMEKVFDDIETNMNLIGATAVEDKLQDQAA ENSCPOP00000000785/1-1002 VAFKEIAPDDYERIDRQLIEAKMALQDREEKLEKVFDDIETNMNLIGATSVEDKLQDQAA ******.***:***: **:************:**:** ***********:********** ENSMUSP00000119320/1-1129 ETIEALHAAGLKVWVLTGDKMETAKSTCYACRLFQTNTELLELTTKTIEESERKEDRLHE ENSRNOP00000048676/1-1129 ETIEALHAAGLKVWVLTGDKMETAKSTCYACRLFQTNTELLELTTKTIEESERKEDRLHE ENSP00000332756/1-1132 ETIEALHAAGLKVWVLTGDKMETAKSTCYACRLFQTNTELLELTTKTIEESERKEDRLHE XP_004862367.1/1-1063 ETIEALHTAGLKVWVLTGDKMETAKSTCYACRLFQTSTELLELTTKTIEESERKEDRLHE ENSCPOP00000000785/1-1002 ETIEALHAAGLKVWVLTGDKMETAKSTCYACRLFQTSTELLELTTKTIEESERKEDRLHE *******:****************************.*********************** ENSMUSP00000119320/1-1129 LLIEYRKKLLHEFPKSTRSLKKAWTEHQEYGLIIDGSTLSLILNSSQDCSSNNYKSIFLQ ENSRNOP00000048676/1-1129 LLIEYRKKLLHEFPKSTRSLKKAWTEHQEYGLIIDGSTLSLILNSSQDCSSNNYKSIFLQ ENSP00000332756/1-1132 LLIEYRKKLLHEFPKSTRSFKKAWTEHQEYGLIIDGSTLSLILNSSQDSSSNNYKSIFLQ XP_004862367.1/1-1063 LLIEYRKKLLHEFPKSARSLKKAWTEHQEYGLIIDGSTLSLILNSSQDSSSNNYKTIFLQ ENSCPOP00000000785/1-1002 LLIEYRKKLLHEFPKSARSLKKAWTDHQEYGLIIDGSTLSLILNSSQDSRSNNYKNIFLQ ****************:**:*****:**********************. *****.**** ENSMUSP00000119320/1-1129 ICMKCTAVLCCRMAPLQKAQIVRMVKNLKGSPITLSIGDGANDVSMILESHVGIGIKGKE ENSRNOP00000048676/1-1129 ICMKCTAVLCCRMAPLQKAQIVRMVKNLKGSPITLSIGDGANDVSMILESHVGIGIKGKE ENSP00000332756/1-1132 ICMKCTAVLCCRMAPLQKAQIVRMVKNLKGSPITLSIGDGANDVSMILESHVGIGIKGKE XP_004862367.1/1-1063 ICMKCTAVLCCRMAPLQKAQIVRMVKNLKGSPITLSIGDGANDVSMILESHVGIGIKGKE ENSCPOP00000000785/1-1002 ICMKCTAVLCCRMAPLQKAQIVRMVKNLKGSPITLSIGDGANDVSMILESHVGIGIKGKE ************************************************************ ENSMUSP00000119320/1-1129 GRQAARNSDYSVPKFKHLKKLLLVHGHLYYVRIAHLVQYFFYKNLCFILPQFLYQFFCGF ENSRNOP00000048676/1-1129 GRQAARNSDYSVPKFKHLKKLLLAHGHLYYVRIAHLVQYFFYKNLCFILPQFLYQFFCGF ENSP00000332756/1-1132 GRQAARNSDYSVPKFKHLKKLLLAHGHLYYVRIAHLVQYFFYKNLCFILPQFLYQFFCGF XP_004862367.1/1-1063 GRQAARNSDYSVPKFKHLKKLLLAHGHLYYVRIAHLVQYFFYKNLCFILPQFLYQFFCGF ENSCPOP00000000785/1-1002 GRQAARNSDYSVPKFKHLKKLLLAHGHLYYVRIAHLVQYFFYKNLCFILPQFLYQFFCGF ***********************.************************************ ENSMUSP00000119320/1-1129 SQQPLYDAAYLTMYNICFTSLPILAYSLLEQHINIDTLTADPRLYMKITGNAMLQLGPFL ENSRNOP00000048676/1-1129 SQQPLYDAAYLTMYNICFTSLPILAYSLLEQHINIDALTADPRLYMKITGNAMLQLGPFL ENSP00000332756/1-1132 SQQPLYDAAYLTMYNICFTSLPILAYSLLEQHINIDTLTSDPRLYMKISGNAMLQLGPFL XP_004862367.1/1-1063 SQQPLYDAAYLTMYNICFTSLPILAYSLLEQHIHIDTLTSDPRLYMKISGNAMLQLGPFL ENSCPOP00000000785/1-1002 SQQPLYDAAYLTMYNICFTSLPILAYSLLEQHIHIDTLTSDPRLYMKISGNAMLQLGPFL *********************************:**:**:********:*********** ENSMUSP00000119320/1-1129 HWTFLAAFEGTVFFFGTYFLFQTSSLEDNGKIYGNWTFGTIVFTVLVFTVTLKLALDTRF ENSRNOP00000048676/1-1129 YWTFLAAFEGTVFFFGTYFLFQTTSLEDNGKIYGNWTFGTIVFTVLVFTVTLKLALDTRF ENSP00000332756/1-1132 YWTFLAAFEGTVFFFGTYFLFQTASLEENGKVYGNWTFGTIVFTVLVFTVTLKLALDTRF XP_004862367.1/1-1063 YWTFLAAFEGTVFFFGTYFLFHTASLEENGKVYGNWTFGTIVFTVLVFTVTLKLALDTRF ENSCPOP00000000785/1-1002 YWTFLAAFEGAVFFFGTYFLFHTASLEENGKVYGNWTFGTIVFTVLVFTVTLKV------ :*********:**********:*:***:***:*********************: ENSMUSP00000119320/1-1129 WTWINHFVIWGSLAFYVFFSFFWGGIIWPFLKQQRMYFVFAQMLCSVSTWLAIILLIFIS ENSRNOP00000048676/1-1129 WTWINHFVIWGSLAFYVFFSFFWGGIIWPFLKQQRMYFVFAQMLSSVSTWLAIILLIFIS ENSP00000332756/1-1132 WTWINHFVIWGSLAFYVFFSFFWGGIIWPFLKQQRMYFVFAQMLSSVSTWLAIILLIFIS XP_004862367.1/1-1063 WTWINHFVIWGSLAFYIFFSFFWGGIIWPFLKQQRMYFVFAQMLSSVSTWLAIILLIFVS ENSCPOP00000000785/1-1002 ------------------------------------------------------------ ENSMUSP00000119320/1-1129 LFPEILLIVVKNVRRRSARRNLSCRRASDSLSARPSVRPLLLRTFSDESNIL ENSRNOP00000048676/1-1129 LFPEILLIVVKNVRRRSARRNLSCRRASDSLSARPSVRPLLLRTFSDESNIL ENSP00000332756/1-1132 LFPEILLIVLKNVRRRSARRNLSCRRASDSLSARPSVRPLLLRTFSDESNVL XP_004862367.1/1-1063 LFPEILLIVLKNVRRRSARRNLNCRRASDSLSTRPSVRPLLLRTFSDESNVL ENSCPOP00000000785/1-1002 ----------------------------------------------------