CLUSTAL W(1.81) multiple sequence alignment ENSMUSP00000085440/1-992 MSSLALSQLLLAVTLPLLELEPTFVPTAQSE----------------------------- ENSRNOP00000034976/1-890 ------------------------------------------------------------ ENSP00000307831/1-1079 MVCSAAPLLLLATTLPLLGSPVAQASQPVSETGVRPREGLQRRQWG-PLIGRDKAWNERI ENSCPOP00000000769/1-1069 MVCLAAPWLLLAAIL-LLGSAVAPVPQTVSMTTV--RRGLQRSQQGRPGVRGSRRWETGS XP_004839194.1/1-991 MVCPAAPRLLLAVTL-LLGSVVAPASQPV------------------------------- ENSMUSP00000085440/1-992 ---------------------------------------LSPYGG--KSGQQLNQYSGEG ENSRNOP00000034976/1-890 ------------------------------------------------------------ ENSP00000307831/1-1079 DRPFPACPIPLSSSFGRWPKGQTMWAQTSTLTLTEEELGQSQAGGESGSGQLLDQENGAG ENSCPOP00000000769/1-1069 RFPVPMCTLDFRQK-AELPRHQSCWTGRASPALFQV---QGQAGE--GPGQQLDHGSGAG XP_004839194.1/1-991 ---------------------------------------QGQAGG--GPGQQLDHQSGAG ENSMUSP00000085440/1-992 ESVLVSSYVHLEFSSTAWPQELSKNFTLPTALAVLPPKT-LTGLGLTTECRANHSGTSLC ENSRNOP00000034976/1-890 --------------------------------------M-ITALVLTTECHVDHSGTSFC ENSP00000307831/1-1079 ESALVSVYVHLDFPDKTWPPELSRTLTLPAASASSSPRPLLTGLRLTTECNVNHKGNFYC ENSCPOP00000000769/1-1069 YSVLVSVYVQLEFSDKTWPLAHHGALTLPPTSATSSPRN-LTSLSISTECNVTRKGHSHC XP_004839194.1/1-991 ESILVSVYVQLEFSDKTWPLD----LALPPASAASSPRN-LTGLSITTDCNVNHTGHSHC :*.* ::*:*.. :.* * ENSMUSP00000085440/1-992 TCHPGYQWNATLCSLYPHCWGRRSERDSCMCRSFHGPVTGYCQLLPP----------VPA ENSRNOP00000034976/1-890 TCHPDYQWNTTLCSLYPNCCGHRSERDSCECLSFHGPVPGYCQLLPP----------VPA ENSP00000307831/1-1079 ACLSGYQWNTSICLHYPPCQSL-HNHQPCGCLVFSHPEPGYCQLLPPGSPVTC-LPAVPG ENSCPOP00000000769/1-1069 ACRPGYQWSDRHCSRTMSCPSHHHNSQPCDCRIFSGSVPGYCQWLPPEKPTLSSAPTVPG XP_004839194.1/1-991 ACRPGYQWSARLCSSSISCPSHRHNHRPCDCRIFSHPVPSYCQLLPPVPLQPCLLPPVPG :* ..***. * * . : .* * * . ..*** *** **. ENSMUSP00000085440/1-992 NLILDSQLQMHGNTLNLILLKKEEATNLRWFLRHSKNHTPISLWPGTNVLQTSSEGQSGL ENSRNOP00000034976/1-890 NLTLDSQLQMHRNTLNLILLKKEKATNLRWYLRQSENHRPILLWPGTNVFQTSNESQAGL ENSP00000307831/1-1079 ILNLNSQLQMPGDTLSLTLHLSQEATNLSWFLRHPGSPSPILLQPGTQVSVTSSHGQAAL ENSCPOP00000000769/1-1069 NLTLNSEPQLPGDKLNLTLLVTHNATNLKWFLRRTDNGKRIPLRSGAQVSLSSGQGQASL XP_004839194.1/1-991 NLSLNSQLQMPGDVLNLTLLTTQNATNPKWFLRRTESSKCIALRSGAQVSLSSHQGQASL * *:*: *: : *.* * ..:*** *:**:. . * * .*::* :* ..*:.* ENSMUSP00000085440/1-992 RVARMSRHWAGEYESIFEAQGFRWRLRQLVKVPLQEEEVVRLPDALSISCTASTGFQLSC ENSRNOP00000034976/1-890 QIAHMSRHWTGEYESIFEAQGFRRRLRQVVKMPLEEKDVVRLPEELSISCAASTGFQLRC ENSP00000307831/1-1079 SVSNMSHHWAGEYMSCFEAQGFKWNLYEVVRVPLKATDVARLPYQLSISCATSPGFQLSC ENSCPOP00000000769/1-1069 SVTCTSSSWAGEYIIYFEAQGFTWRLQQVVKVPLQTTEVVLFPDQLSISCDASPGFQLSC XP_004839194.1/1-991 SVSHPSHRWAGEYIIYFEAQGFIWKLQQEVKVPLQKAEVARFPDELSIACAASPGFQLSC :: * *:*** ****** .* : *::**: :*. :* ***:* :*.**** * ENSMUSP00000085440/1-992 CIPLTT-DYTATWSPGEDSQASLQKMSDSQCFVLAVPHCPATNTTYTCTLQSQNLPPLVA ENSRNOP00000034976/1-890 CIPLTNMAYTATWSPGEDSQASLQNMPDSQCFVLAVRHCPAANTTYTCTLQSQSLAPLVA ENSP00000307831/1-1079 CIPSTNLAYTAAWSPGEGSKASSFNESGSQCFVLAVQRCPMADTTYACDLQSLGLAPLRV ENSCPOP00000000769/1-1069 CFPSTNLDYTAAWSPREDSQVSLVNRKDSRCLLLDVQRCPEANTMYTCVLESPGLAPLRR XP_004839194.1/1-991 CFPSTNLVYTAAWSPREGSQVSLIHRTGSQCLLLDVQHCPEANTTYTCVLESQGLDPLRR *:* *. ***:*** *.*:.* : .*:*::* * :** ::* *:* *:* .* ** ENSMUSP00000085440/1-992 PVSITIIQDGDTTCPEDFSVVSWNVTKAGFVAQAPCPVNKKGVVKRLCGTDGIWRPVQNT ENSRNOP00000034976/1-890 PVSITIIQDGDTTCPEDFSVVAWNVTKAGFMAQAPCPMNKTGVVKRLCGSNGIWGPVQDS ENSP00000307831/1-1079 PISITIIQDGDITCPEDASVLTWNVTKAGHVAQAPCPESKRGIVRRLCGADGVWGPVHSS ENSCPOP00000000769/1-1069 SVAVTIIQDGDIVCPDDFSEAAWKVTKAGHVAQVPCPMDKTGMVARPCGPDGVWGPVWNS XP_004839194.1/1-991 SVAVTIIRDGDIACPEDFSAVAWNVTKAGHVAQVPCPVNKAGTVKRLCGPDGAWGPVQHN .:::***:*** .**:* * :*:*****.:**.*** .* * * * **.:* * ** . ENSMUSP00000085440/1-992 CTEAKILTLCLKAKLLLEGQGKPYEEVPWILSELQEQVGVASTPSDLWEMLHTVTLLAKV ENSRNOP00000034976/1-890 CTEAKILDLYSKAKLLLEGQGKPNEQVPRILRELQRQVGVVSTPSDLREMLHTVTLLAKV ENSP00000307831/1-1079 CTDARLLALFTRTKLLQAGQGSPAEEVPQILAQLPGQAAEASSPSDLLTLLSTMKYVAKV ENSCPOP00000000769/1-1069 CTDTRILALYEEARLLQGGQGKPNNKVPQILAKLQDYAEETASPSDFRKLLSTVKILAEV XP_004839194.1/1-991 CTDVGILALYDEARLLQAGQGKPDRRVPQILERLQERAEVTSSPSDLLKLLSTVEVLADV **:. :* * .::** ***.* ..** ** .* . .::***: :* *: :*.* ENSMUSP00000085440/1-992 VAETSTELTGSALKDLLTTTDKILDANISALWTLAQAQEPSMGSDFLKAVETLVHSLRPQ ENSRNOP00000034976/1-890 VAETSTELTDRALKDLLTTTDKILDVNISSLWTLARAQEPSMGSDFLKAVETLVHSVSPQ ENSP00000307831/1-1079 VAEARIQLDRRALKNLLIATDKVLDMDTRSLWTLAQARKPWAGSTLLLAVETLACSLCPQ ENSCPOP00000000769/1-1069 VAEAGTALKPSALKDLLTLTDKVLDTNTSSLWTRAQAQEPEMGSYFLQALETLVCSLSPK XP_004839194.1/1-991 VAEVRTALTPSALKDLLTITDKVLDTNVSSLWTLAQAQEPSMGSDFLLAVETLARSLCPK ***. * ***:** ***:** : :*** *:*::* ** :* *:***. *: *: ENSMUSP00000085440/1-992 QHPFSFSSANVLLQSQLLRHSSPPGYQMSFSTWPLLQARIPWHSLAPLVHSGTNVSITSL ENSRNOP00000034976/1-890 QHPFSFSSSNVLLQSQLLRHSSPLGYQMP-SAPPLLQARIPWHSLAPLVLNGTNVRITSL ENSP00000307831/1-1079 DHPFAFSLPNVLLQSQLFGPTFPADYSISFPTRPPLQAQIPRHSLAPLVRNGTEISITSL ENSCPOP00000000769/1-1069 DQPFSFSSSNVLLQAQLLDPTSAGDYHTSFSTQPPLKAWIPRNSLSPLVHNGTNVSVTSL XP_004839194.1/1-991 DQPFSFSSSNVLLQSELLEPPLAGDYQISFSTQPPLWVRIPRYALTPLVHNGTSVSVTGL ::**:** .*****::*: . . .* . .: * * . ** :*:*** .**.: :*.* ENSMUSP00000085440/1-992 VLQKLDYRLPSNYTQGLWNTPYTTPGLILVVSITADGQAFTQAEVIMDYEDMNGTLHCVF ENSRNOP00000034976/1-890 ALQKLDSRLPSNYRQGLRDTSYATPGMILVISITADGQDFTQAEVIMDFEDMNGTLHCVF ENSP00000307831/1-1079 VLRKLDHLLPSNYGQGLGDSLYATPGLVLVISIMAGDRAFSQGEVIMDFGNTDGSPHCVF ENSCPOP00000000769/1-1069 VLQKLDQRLPYNYEQVLGDLQHATPGLVLVIAIMAGGKAFTQTEVIMDFGQTGGTLRCVF XP_004839194.1/1-991 VLQNLDHLLPSNSRQGLGDLQYGTPGLVLVISIMADGKAFTQAEVIMDFGQTHGALHCVF .*::** ** * * * : : ***::**::* *..: *:* *****: : *: :*** ENSMUSP00000085440/1-992 WDHRVFQGQGGWSDEGCEVHAANAS-ITQCICQHLTAFSILMSQHTVPENPTLDLLSQVG ENSRNOP00000034976/1-890 WDHNAFQGRGGWSDEGCELQAANAS-AVQCVCRHLTAFSILMSQHAVPEDPLLDLLSQVG ENSP00000307831/1-1079 WDHSLFQGRGGWSKEGCQAQVASASPTAQCLCQHLTAFSVLMSPHTVPEEPALALLTQVG ENSCPOP00000000769/1-1069 WDYHLFQHAGGWSDKGCQARAADGSIATQCICQHLTAFSVLMSRYPVPECPVLKHLSRVG XP_004839194.1/1-991 WDHSLFQHVGGWSDSGCQAQAADDGLATQCICQHLTAFSTLMSRHTVPENPVLELLTQVG **: ** ****..**: :.*. . .**:*:****** *** :.*** * * *::** ENSMUSP00000085440/1-992 TGASVLALLVCLAIYGLVWRVVVRNKVAFFRHTTLFNMVICLLVADTCFLGSPFLPSGYH ENSRNOP00000034976/1-890 VGASILALLVCLVIYRLVWRVVVRNKVAFFRHTALFNMVICLLVADTCFLGNPWLPSGYH ENSP00000307831/1-1079 LGASILALLVCLGVYWLVWRVVVRNKISYFRHAALLNMVFCLLAADTCFLGAPFLSPGPR ENSCPOP00000000769/1-1069 LSTSILALLVCLGVYRLVWRAVVQNKVAFFRHAALFNMAICLLIADTWFLVSSVFLAGTQ XP_004839194.1/1-991 LGASILALLVCLTVYRLVWRAVVRNKVAFFRHAALLNMAICLLAADTWYLVGSVFLPGTQ .:*:******* :* ****.**:**:::***::*:**.:*** *** :* . : .* : ENSMUSP00000085440/1-992 SLICLVTAFLCHFFYLATFFWMLAQALVLAHQLLFVFHQLSKHVVLSLMVMLGYLCPLGF ENSRNOP00000034976/1-890 SLVCLATAFLCHFFYLATFFWMLAQALVLAHQLLFVFHQLSKPLVLSMMSILGYLCPLGF ENSP00000307831/1-1079 SPLCLAAAFLCHFLYLATFFWMLAQALVLAHQLLFVFHQLAKHRVLPLMVLLGYLCPLGL ENSCPOP00000000769/1-1069 DVLCLAIAFLCHFFYLATFFWMLAQALLLAHQLLFVFHHLSKSLVLSLMVTLGYLCPLGL XP_004839194.1/1-991 DLLCLATAFLCHFFYLGTFFWMLAQALLLAHQLLFVFHQLSKHLILSLMVILGYLCPLGF . :**. ******:**.**********:**********:*:* :*.:* ********: ENSMUSP00000085440/1-992 AGVTLGLYLPQRKYLWEGKCFLNGGGVMLYSFSEPVLAIVGVNGLVLVIAVLKLLRPSLS ENSRNOP00000034976/1-890 AGVTLGLYLPQRKYLREGKCLLSGDGVSLHAFSEPVLAIVSVNGLVLVIAVLKLLRPSLS ENSP00000307831/1-1079 AGVTLGLYLPQGQYLREGECWLDGKGGALYTFVGPVLAIIGVNGLVLAMAMLKLLRPSLS ENSCPOP00000000769/1-1069 AGVTLGLYLPRGQYLSEDTCWLDWKSGAIYTFVGPVLTIVGVNGLVLATTVLKLLRPSLS XP_004839194.1/1-991 AGVTLGLYLPRGQYLREGQCWLDGKGSAVYTFVGPVLAIVGVNGLVLAMTVLKLLRPSLS **********: :** *. * *. . :::* ***:*:.******. ::********* ENSMUSP00000085440/1-992 EGPTVEKRQALVGVLKALLILTPIFGLTWGLGVATLFDG-SIVSHYAFSILNSLQGVFIL ENSRNOP00000034976/1-890 EGPAVEKRQALVGVLKALLILTPIFGLTWGLGVTTLFEG-SLVFHYIFVILNSLQ----- ENSP00000307831/1-1079 EGPPAEKRQALLGVIKALLILTPIFGLTWGLGLATLLEEVSTVPHYIFTILNTLQGVFIL ENSCPOP00000000769/1-1069 EGPPAEKRQALTGVLKALLILTPIFGITWGLGLVTMTEETSVVPHYIFVTLNTFQGVFIL XP_004839194.1/1-991 EGPSVEKRQALLGVLKALLILTPIFGITWGLGLATMLEEASAIPHYIFVILNSSQGVFIL ***..****** **:***********:*****:.*: : * : ** * **: * ENSMUSP00000085440/1-992 VFGCLTDKKVLEALRKRLRGSRSSNSAISMVT----NETYTSEHSKERSEPASYEERMTD ENSRNOP00000034976/1-890 ---------VLEALRKWLRGSRSSNSAISMVT----NESCTSEHSRERSELASYEEQMAD ENSP00000307831/1-1079 LFGCLMDRKIQEALRKRFCRAQAPSSTISLVSCCLQILSCASKSMSEGIPWPSSEDMGTA ENSCPOP00000000769/1-1069 LFGCLMDKKVQEALRKYFCHARSPSSASSLVSCWLQGPRCLPRRSEGTHNLP---EMGTA XP_004839194.1/1-991 WFGCLIDKKVQEALRKRFCHTRHPSSNISLAT----NETCCSEQSRGGSQ--------TA : ***** : :: ..* *:.: .. : ENSMUSP00000085440/1-992 -- ENSRNOP00000034976/1-890 -- ENSP00000307831/1-1079 RS ENSCPOP00000000769/1-1069 RC XP_004839194.1/1-991 R-