CLUSTAL W(1.81) multiple sequence alignment ENSCPOP00000000693/1-1695 MAPGSRWRPPPP-PLLLLVVLLAAGAGGLEFGGGPGQWARYARWTGAASSGELSFSLRTN ENSRNOP00000063600/1-1198 MALGSRWRPPPQLPPLLLLLALVAGVRGLEFGGGPGQWARYARWAGAASTGELSFSLRTN XP_004852535.1/1-1704 MAPGSRWQPPPP-PLLLLVFVLAAGAGGLEFGGGPGQWARYARWAGAASSGELSFSLRTN ENSP00000366774/1-1712 MASGSRWRPTPPPLLLLLLLALAARADGLEFGGGPGQWARYARWAGAASSGELSFSLRTN ENSMUSP00000119762/1-1710 MALGSRWQPPPQLPPLLLLLALAAGVRGLEFGGGPGQWARYARWAGAASTGELSFSLRTN ** ****:*.* ***:. *.* . *****************:****:********** ENSCPOP00000000693/1-1695 ATRALLLYLDDGGDCDFLELLLVDGRLRLRFTLSCAEPATLQLDTPVADDRWHMVLLTRD ENSRNOP00000063600/1-1198 ATRALLLYLDDGGDCDFLELLLVDGRLRLRFTLSCAEPATLQLDTPVADDRWHMVLLTRD XP_004852535.1/1-1704 TTRALLLYLDDGGDCDFLELLLVDGRLRLRFTLSCAEPATLQLDTPVADDRWHMVLLTRD ENSP00000366774/1-1712 ATRALLLYLDDGGDCDFLELLLVDGRLRLRFTLSCAEPATLQLDTPVADDRWHMVLLTRD ENSMUSP00000119762/1-1710 ATRALLLYLDDGGDCDFLELLLVDGRLRLRFTLSCAEPATLQLDTPVADDRWHMVLLTRD :*********************************************************** ENSCPOP00000000693/1-1695 ARRTALAVDGEARAAEVRSKRREMQVASDLFVGGIPPDVRLSALTLSTAKYEPPFRGLLA ENSRNOP00000063600/1-1198 ARRTALAVDGEARAAEVRSKRREMQVASDLFVGGIPPDVRLSALTLSTVKYEPPFRGLLA XP_004852535.1/1-1704 ARRTALAVDGEARAAEVRSKRREMQVASDLFVGGIPPDVRLSALTLSTAKYEPPFRGLLA ENSP00000366774/1-1712 ARRTALAVDGEARAAEVRSKRREMQVASDLFVGGIPPDVRLSALTLSTVKYEPPFRGLLA ENSMUSP00000119762/1-1710 ARRTALAVDGEARAAEVRSKRREMQVASDLFVGGIPPDVRLSALTLSTVKYEPPFRGLLA ************************************************.*********** ENSCPOP00000000693/1-1695 NLKLGERPPALLGSQGLRGAAADPLCAPVRNPCANGGLCTVLAPGEVGCDCSHTGFGGKF ENSRNOP00000063600/1-1198 NLKLGERPPALLGSQGLRGAAADPLCAPARNPCANGGLCTVLAPGEVGCDCSHTGFGGKF XP_004852535.1/1-1704 NLKLGERPPALLGSQGLRGAAADPLCAPARNPCANGGLCTVLAPGEVGCDCSHTGFSGKF ENSP00000366774/1-1712 NLKLGERPPALLGSQGLRGATADPLCAPARNPCANGGLCTVLAPGEVGCDCSHTGFGGKF ENSMUSP00000119762/1-1710 NLKLGERPPALLGSQGLRGAAADPLCAPARNPCANGGLCTVLAPGEVGCDCSHTGFGGKF ********************:*******.***************************.*** ENSCPOP00000000693/1-1695 CSEEEHPMEEGPAHLTLNSEVGSLLFS----GRGGAGDVHQPTKGKEEFVATFKGNEFFC ENSRNOP00000063600/1-1198 CSEGE-PRQEGPAHLTLNSEVGSLLFSEGGAGRGGAGDVHQPTKGKEEFVATFKGNEFFC XP_004852535.1/1-1704 CSEEEHPM-EGPAHLTLNSEVGSLLFSEGGAGRGGASDVHQPTKGKEEFVATFKGNEFFC ENSP00000366774/1-1712 CSEEEHPM-EGPAHLTLNSEVGSLLFSEGGAGRGGAGDVHQPTKGKEEFVATFKGNEFFC ENSMUSP00000119762/1-1710 CSEEEHPM-EGPAHLTLNSEVGSLLFSEGGAGRGGAGDVHQPTKGKEEFVATFKGNEFFC *** * * ****************** *****.*********************** ENSCPOP00000000693/1-1695 YDLSHNPIQSSTDEITLAFRTLQRNGLMLHTGKSADYVNLSLKSGAVWLVINLGSGAFEA ENSRNOP00000063600/1-1198 YDLSHNPIQSSTDEITLAFRTLQRNGLMLHTGKSADYVNLSLKSGAVWLVINLGSGAFEA XP_004852535.1/1-1704 YDLSHNPIQSSTDEITLAFRTLQRNGLMLHTGKSADYVNLSLKSGAVWLVINLGSGAFEA ENSP00000366774/1-1712 YDLSHNPIQSSTDEITLAFRTLQRNGLMLHTGKSADYVNLSLKSGAVWLVINLGSGAFEA ENSMUSP00000119762/1-1710 YDLSHNPIQSSTDEITLAFRTLQRNGLMLHTGKSADYVNLSLKSGAVWLVINLGSGAFEA ************************************************************ ENSCPOP00000000693/1-1695 LVEPVNGKFNDNAWHDVRVTRNLRQHAGIGHAMVNKLHYLVTISVDGILTTTGYTQEDYT ENSRNOP00000063600/1-1198 LVEPVNGKFNDNAWHDVRVTRNLRQHAGIGHAMVNKLHYLVTISVDGILTTTGYTQEDYT XP_004852535.1/1-1704 LVEPVNGKFNDNAWHDVRVTRNLRQHAGIGHAM-------VTISVDGILTTTGYTQEDYT ENSP00000366774/1-1712 LVEPVNGKFNDNAWHDVRVTRNLRQHAGIGHAMVNKLHYLVTISVDGILTTTGYTQEDYT ENSMUSP00000119762/1-1710 LVEPVNGKFNDNAWHDVRVTRNLRQHAGIGHAMVNKLHYLVTISVDGILTTTGYTQEDYT ********************************* ******************** ENSCPOP00000000693/1-1695 MLGSDDFFYIGGSPNTADLPGSPVSNNFMGCLKDVVYKNNDFKLELSRLAKEGDPKMKLQ ENSRNOP00000063600/1-1198 MLGSDDFFYIGGSPNTADLPGSPVSNNFMGCLKDVVYKNNDFKLELSRLAKEGDPKMKLQ XP_004852535.1/1-1704 MLGSDDFFYIGGSPNTADLPGSPVSNNFMGCLKDVVYKNNDFKLELSRLAKEGDPKMKLQ ENSP00000366774/1-1712 MLGSDDFFYIGGSPNTADLPGSPVSNNFMGCLKDVVYKNNDFKLELSRLAKEGDPKMKLQ ENSMUSP00000119762/1-1710 MLGSDDFFYIGGSPNTADLPGSPVSNNFMGCLKDVVYKNNDFKLELSRLAKEGDPKMKLQ ************************************************************ ENSCPOP00000000693/1-1695 GDLSFRCEDVAALDPVTFESPEAFVALPRWSAKRTGSISLDFRTTEPNGLLLFSQGRRAG ENSRNOP00000063600/1-1198 GDLSFRCEDVAALDPVTFESPEAFVALPRWSAKRTGSISLDFRTTEPNGLLLFSQGRRAG XP_004852535.1/1-1704 GDLSFHCEDVAALDPVTFESPEAFVALPRWSAKRTGSISLDFRTTEPNGLLLFSQGQRPG ENSP00000366774/1-1712 GDLSFRCEDVAALDPVTFESPEAFVALPRWSAKRTGSISLDFRTTEPNGLLLFSQGRRAG ENSMUSP00000119762/1-1710 GDLSFRCEDVAALDPVTFESPEAFVALPRWSAKRTGSISLDFRTTEPNGLLLFSQGRRAG *****:**************************************************:*.* ENSCPOP00000000693/1-1695 AGPGSHSSAQRADYFAMELLDGYLYLLLDMGSGGIKLRASSRKVNDGEWCHVDFQRDGRK ENSRNOP00000063600/1-1198 AGVGSHSSSQRADYFAMELLDGYLYLLLDMGSGGIKLRASSRKVNDGEWCHVDFQRDGRK XP_004852535.1/1-1704 AGPGSHGSAQRADYFAMELLDGYLYLLLDMGSGGIKLRASSRKVNDGEWCHVDFQRDGRK ENSP00000366774/1-1712 GGAGSHSSAQRADYFAMELLDGHLYLLLDMGSGGIKLRASSRKVNDGEWCHVDFQRDGRK ENSMUSP00000119762/1-1710 AGVGSHSSTQRADYFAMELLDGYLYLLLDMGSGGIKLRASSRKVNDGEWCHVDFQRDGRK .* ***.*:*************:************************************* ENSCPOP00000000693/1-1695 GSISVNSRSTPFLATGESEILDLESELYLGGLPEGGRVDLPLPPEVWTAALRAGYVGCVR ENSRNOP00000063600/1-1198 GSISVNSRSTPFLATGESEVLDLESELYLGGLPEGGRVDLPLPPEVWTAALRAGYVGCVR XP_004852535.1/1-1704 GSISVNSRSTPFLATGESEILDLESELYLGGLPEGGRVDLPLPPEVWTAALRAGYVGCVR ENSP00000366774/1-1712 GSISVNSRSTPFLATGDSEILDLESELYLGGLPEGGRVDLPLPPEVWTAALRAGYVGCVR ENSMUSP00000119762/1-1710 GSISVNSRSTPFLATGESEVLDLESELYLGGLPEGGRVDLPLPPEVWTAALRAGYVGCVR ****************:**:**************************************** ENSCPOP00000000693/1-1695 DLFIDGRSRDLRGLAEAQGAVGVAPFCSRETLKQCASAPCRNGGICREGWNRFVCDCIGT ENSRNOP00000063600/1-1198 DLFIDGRSRDLRGLAEAQGAVGVAPFCSRETLKQCASAPCRNGGICREGWNRFVCDCIGT XP_004852535.1/1-1704 DLFIDGRSRDLRGLAEAQGAVGVAPFCSRETLKQCASAPCHNGGICREGWNRFVCDCIGT ENSP00000366774/1-1712 DLFIDGRSRDLRGLAEAQGAVGVAPFCSRETLKQCASAPCRNGGVCREGWNRFICDCIGT ENSMUSP00000119762/1-1710 DLFIDGRSRDLRGLAEAQGAVGVAPFCSRETLKQCASAPCRNGGICREGWNRFVCDCIGT ****************************************:***:********:****** ENSCPOP00000000693/1-1695 GFLGRVCEREATVLSYDGSMYMKIMLPNAMHTEAEDVSLRFMSQRAYGLMMATTSRESAD ENSRNOP00000063600/1-1198 GFLGRVCEREATVLSYDGSMYMKIMLPNAMHTEAEDVSLRFMSQRAYGLMMATTSRESAD XP_004852535.1/1-1704 GFLGRVCEREATVLSYDGSMYMKIMLPNAMHTEAEDVSLRFMSQRAYGLMMATTSRESAD ENSP00000366774/1-1712 GFLGRVCEREATVLSYDGSMYMKIMLPNAMHTEAEDVSLRFMSQRAYGLMMATTSRESAD ENSMUSP00000119762/1-1710 GFLGRVCEREATVLSYDGSMYMKIMLPTAMHTEAEDVSLRFMSQRAYGLMMATTSRESAD ***************************.******************************** ENSCPOP00000000693/1-1695 TLRLELDGGQMKLTVNLDCLRVGCAPS---KGPETLFAGHKLNDNEWHTVRVVRRGKSLQ ENSRNOP00000063600/1-1198 TLRLELDGGQMKLTVNLDCLRVGCAPSAAGKGPETLFAGHKLNDNEWHTVRVVRRGKSLQ XP_004852535.1/1-1704 TLRLELDGGQMKLTVNLDCLRVGCAPS---KGPETLFAGHKLNDNEWHTVRVVRRGKSLQ ENSP00000366774/1-1712 TLRLELDGGQMKLTVNLDCLRVGCAPS---KGPETLFAGHKLNDNEWHTVRVVRRGKSLQ ENSMUSP00000119762/1-1710 TLRLELDGGQMRLTVNLDCLRVGCAPS---KGPETLFAGHKLNDNEWHTVRVVRRGKSLQ ***********:*************** ****************************** ENSCPOP00000000693/1-1695 LSVDNVTVEGQMAGAHTRLEFQNIETGIMTERRFISVVPSNFIGHLSGLVFNGQPYMDQC ENSRNOP00000063600/1-1198 LSVDNVTVEGQMAGAHTRLEFHNIETGIMTERRFISVVPSNFIGHLSGLVFNGQPYMDQC XP_004852535.1/1-1704 LSVDNVTVEGQMAGAHTRLEFHNIETGIMTERRFISVVPSNFIGHLSGLVFNGQPYMDQC ENSP00000366774/1-1712 LSVDNVTVEGQMAGAHMRLEFHNIETGIMTERRFISVVPSNFIGHLSGLVFNGQPYMDQC ENSMUSP00000119762/1-1710 LSVDNVTVEGQMAGAHTRLEFHNIETGIMTERRFISVVPSNFIGHLSGLVFNGQPYMDQC **************** ****:************************************** ENSCPOP00000000693/1-1695 KDGDITYCELNARFGLRAIVADPVTFKSRSSYLALATLQAYASMHLFFQFKTTAPDGLLL ENSRNOP00000063600/1-1198 KDGDITYCELNARFGLRAIVADPVTFKSRSSYLALATLQAYASMHLFFQFKTTAPDGLLL XP_004852535.1/1-1704 KDGDITYCELNARFGLRAIVADPVTFKSRSSYLALATLQAYASMHLFFQFKTTAPDGLLL ENSP00000366774/1-1712 KDGDITYCELNARFGLRAIVADPVTFKSRSSYLALATLQAYASMHLFFQFKTTAPDGLLL ENSMUSP00000119762/1-1710 KDGDITYCELNARFGLRAIVADPVTFKSRSSYLALATLQAYASMHLFFQFKTTAPDGLLL ************************************************************ ENSCPOP00000000693/1-1695 FNSGNGNDFIVIELVKGYIHYVFDLGNGPSLMKGNSDKPVNDNQWHNVVVSRDPGNVHTL ENSRNOP00000063600/1-1198 FNSGNGNDFIVIELVKGYIHYVFDLGNGPSLMKGNSDKPVNDNQWHNVVVSRDPGNVHTL XP_004852535.1/1-1704 FNSGNGNDFIVIELVKGYIHYVFDLGNGPSLMKGNSDKPVNDNQWHNVVVSRDPGNVHTL ENSP00000366774/1-1712 FNSGNGNDFIVIELVKGYIHYVFDLGNGPSLMKGNSDKPVNDNQWHNVVVSRDPGNVHTL ENSMUSP00000119762/1-1710 FNSGNGNDFIVIELVKGYIHYVFDLGNGPSLMKGNSDKPVNDNQWHNVVVSRDPGNVHTL ************************************************************ ENSCPOP00000000693/1-1695 KIDSRTVTQHSNGARNLDLKGELYIGGLSKNMFSNLPKLVASRDGFQGCLASVDLNGRLP ENSRNOP00000063600/1-1198 KIDSRTVTQHSNGARNLDLKGELYIGGLSKNMFSNLPKLVASRDGFQGCLASVDLNGRLP XP_004852535.1/1-1704 KIDSRTVTQHSNGARNLDLKGELYIGGLSKNMFSNLPKLVASRDGFQGCLASVDLNGRLP ENSP00000366774/1-1712 KIDSRTVTQHSNGARNLDLKGELYIGGLSKNMFSNLPKLVASRDGFQGCLASVDLNGRLP ENSMUSP00000119762/1-1710 KIDSRTVTQHSNGARNLDLKGELYIGGLSKNMFSNLPKLVASRDGFQGCLASVDLNGRLP ************************************************************ ENSCPOP00000000693/1-1695 DLIADALHRIGQVERGCDGPSTTCTEESCANQGVCLQQWDGFTCDCTMTSYGGPICNDPG ENSRNOP00000063600/1-1198 DLIADALHRIGQVERGCDAPSTACPSSPAAGTGVGQRERTGFPGLCRMCYYGGDSCHTSG XP_004852535.1/1-1704 DLIADALHRIGQVERGCDGPSTTCTEESCANQGVCLQQWDGFTCDCTMTSYGGPVCNDPG ENSP00000366774/1-1712 DLIADALHRIGQVERGCDGPSTTCTEESCANQGVCLQQWDGFTCDCTMTSYGGPVCNDPG ENSMUSP00000119762/1-1710 DLIADALHRIGQVERGCDGPSTTCTEESCANQGVCLQQWDGFTCDCTMTSYGGPVCNDPG ******************.***:*.....*. ** :: **. * * *** *: .* ENSCPOP00000000693/1-1695 TTYIFGKGGALITYTWPPNDRPSTRMDRLAVGFSTHQRSAVLVRVDSASGLGDYLQLHID ENSRNOP00000063600/1-1198 TTYIFGKGGALITYTWPPNDRPSTRMDRLAVGFSTHQRSAVLVRVDSASGLGDYLQLHI- XP_004852535.1/1-1704 TTYIFGKGGALITYTWPPNDRPSTRMDRLAVGFSTHQRSAVLVRVDSASGLGDYLQLHID ENSP00000366774/1-1712 TTYIFGKGGALITYTWPPNDRPSTRMDRLAVGFSTHQRSAVLVRVDSASGLGDYLQLHID ENSMUSP00000119762/1-1710 TTYIFGKGGALITYTWPPNDRPSTRMDRLAVGFSTHQRSAVLVRVDSASGLGDYLQLHID *********************************************************** ENSCPOP00000000693/1-1695 QGTVGVIFNVGTDDITIDEPNAIVSDGKYHVVRFTRSGGNATLQVDSWPVNERYPAGNFD ENSRNOP00000063600/1-1198 ------------------------------------------------------------ XP_004852535.1/1-1704 QGTVGVIFNVGTDDITIDEPNAIVSDGKYHVVRFTRSGGNATLQVDSWPVNERYPAGNFD ENSP00000366774/1-1712 QGTVGVIFNVGTDDITIDEPNAIVSDGKYHVVRFTRSGGNATLQVDSWPVNERYPAGNFD ENSMUSP00000119762/1-1710 QGTVGVIFNVGTDDITIDEPNAIVSDGKYHVVRFTRSGGNATLQVDSWPVNERYPAGNFD ENSCPOP00000000693/1-1695 NERLAIARQRIPYRLGRVVDEWLLDKGRQLTIFNSQAAIKIGGRDQGRPFQGQVSGLYYN ENSRNOP00000063600/1-1198 ------------------------------------------------------------ XP_004852535.1/1-1704 NERLAIARQRIPYRLGRVVDEWLLDKGRQLTIFNSQAAIKIGGRDQGRPFQGQVSGLYYN ENSP00000366774/1-1712 NERLAIARQRIPYRLGRVVDEWLLDKGRQLTIFNSQAAIKIGGRDQGRPFQGQVSGLYYN ENSMUSP00000119762/1-1710 NERLAIARQRIPYRLGRVVDEWLLDKGRQLTIFNSQAAIKIGGRDQGRPFQGQVSGLYYN ENSCPOP00000000693/1-1695 GLKVLALAAESDPNVRTEGHLRLVGEGPSVLLSAETTATTLLA----------------- ENSRNOP00000063600/1-1198 ------------------------------------------------------------ XP_004852535.1/1-1704 GLKVLALAAESDPNVRTEGHLRLVGEGPSVLLSAETTATTLLADMATTIMETTTTMATTT ENSP00000366774/1-1712 GLKVLALAAESDPNVRTEGHLRLVGEGPSVLLSAETTATTLLADMATTIMETTTTMATTT ENSMUSP00000119762/1-1710 GLKVLALAAESDPNVRTEGHLRLVGEGPSVLLSAETTATTLLADMATTIMETTTTMATTT ENSCPOP00000000693/1-1695 ARRGRSPTLRDSTTQNTDDLLVASAECPSDDEDLEECEPSTGGHVLSATVPEHSLLSPRQ ENSRNOP00000063600/1-1198 ------------------------------------------------------------ XP_004852535.1/1-1704 TRRGRSPTLRDSTTQNTDDLLVASAECPSDDEDLEECEPSTGGELILPIITEDSLDPPPV ENSP00000366774/1-1712 TRRGRSPTLRDSTTQNTDDLLVASAECPSDDEDLEECEPSTGGELILPIITEDSLDPPPV ENSMUSP00000119762/1-1710 TRRGRSPTMRDSTTQNTDDLLVASAECPSDDEDLEECEPSTGGELILPIITEDSLDPPPV ENSCPOP00000000693/1-1695 TTQDPSQTLSPPPRDRPTEPGLGLTLGLEPSTLALQPRVGEVLSASHRNSVTQQVCSLPV ENSRNOP00000063600/1-1198 ------------------------------------------------------------ XP_004852535.1/1-1704 ATRSP--FVPPPPTFYPFLPGVGATQDTLPPPAARRPPPGGPCQAEHDDSDCEEPIEASG ENSP00000366774/1-1712 ATRSP--FVPPPPTFYPFLTGVGATQDTLPPPAARRPPSGGPCQAERDDSDCEEPIEASG ENSMUSP00000119762/1-1710 ATRSP--FVPPPPTFYPFLTGVGATQDTLPPPAARRPSSGGPCQAERDDSDCEEPVEASG ENSCPOP00000000693/1-1695 IRGPEAVKPWLGPGGESGDQSFHPSYLPAISRASPPPPQSPAGDPCLLQ---CVSSSILH ENSRNOP00000063600/1-1198 ------------------------------------------------------------ XP_004852535.1/1-1704 FASGEVFDSSLPP---TDDEDFYTTFPLVTDRTTLLSPRKPAPRPNLRTDGATGAPGVLL ENSP00000366774/1-1712 FASGEVFDSSLPP---TDDEDFYTTFPLVTDRTTLLSPRKPAPRPNLRTDGATGAPGVLF ENSMUSP00000119762/1-1710 FASGEVFDSSLPP---TDDEDFYTTFPLVTDRTTLLSPRKP--RPNLRTDGATGAPGVLF ENSCPOP00000000693/1-1695 GPSVLTPGGGNSSSVLGEREPSEPESQSPREVPRASEPQPLKARRSPPRRRG-PSTPGFP ENSRNOP00000063600/1-1198 ------------------------------------------------------------ XP_004852535.1/1-1704 APSV--PAPNLPAGKMNHRDPLQPLLENPPPGPGA--PTSFEPRRPPPLRPGVTSAPGFP ENSP00000366774/1-1712 APSA--PAPNLPAGKMNHRDPLQPLLENPPLGPGA--PTSFEPRRPPPLRPGVTSAPGFP ENSMUSP00000119762/1-1710 APSA--PAPNLPAGKMNHRDPLQPLLENPPLGPGV--PTAFEPRRPPPLRPGVTSAPGFP ENSCPOP00000000693/1-1695 GLPTSQPHGRGS-GSPGAVEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGS ENSRNOP00000063600/1-1198 ------------------------------------------------------------ XP_004852535.1/1-1704 PLPTANPTGPGERGPPGAVEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGS ENSP00000366774/1-1712 HLPTANPTGPGERGPPGAVEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGS ENSMUSP00000119762/1-1710 RLPTANPTGPGERGPPGAVEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGS ENSCPOP00000000693/1-1695 YQVDQSRNYISNSAQSNGAVVKEKAQAAPKTPSKTKKNKDKEYYV ENSRNOP00000063600/1-1198 --------------------------------------------- XP_004852535.1/1-1704 YQVDQSRNYISNSAQSNGAVVKEKAPAAPKTPSKTKKNKDKEYYV ENSP00000366774/1-1712 YQVDQSRNYISNSAQSNGAVVKEKAPAAPKTPSKAKKNKDKEYYV ENSMUSP00000119762/1-1710 YQVDQSRNYISNSAQSNGAVVKEKAPAAPKTPSKAKKNKDKEYYV