CLUSTAL W(1.81) multiple sequence alignment ENSMUSP00000124179/1-1131 MRSRSSNAEGSAPKQIPRHSKFQDSIQ---DMKHRTHKKDPSCESEGVLPRPVSEKSHTG ENSRNOP00000045927/1-1129 MRSRSSNTEGLAPKQISRRSKFQDTFQ---DMKHRAQKRDPSSESEEALPCPVSEKSCSG ENSP00000346560/1-1135 MRSRGSDTEGSAQKKFPRHTK-GHSFQGPKNMKHRQQDKDSPSESDVILPCPKAEKPHSG ENSCPOP00000000387/1-1127 MRSRSSDIEGSAQKQAPRHTK-DHSFL---DMKHRQQEKDPTSASDEFLPHPNSEKSQGG XP_004858017.1/1-1128 MRSRINDIEGSAQKQVPRHTK-DHSFL---DMKHRKQEKDPTSASDAFPPHPKSEKSQGG **** .: ** * *: .*::* .:: :**** :.:*... *: * * :**. * ENSMUSP00000124179/1-1131 KGHHTEDLSRDDLLFLLSILEGELQARDEVIGILRAEKIDLALLEAQYGFVTPKKVLEAL ENSRNOP00000045927/1-1129 KGHQTEDLSRDDLLFLLSILEGELQARDEVIGILRAEKIDLALLEAHYGFVTPKKVLEAL ENSP00000346560/1-1135 NGHQAEDLSRDDLLFLLSILEGELQARDEVIGILKAEKMDLALLEAQYGFVTPKKVLEAL ENSCPOP00000000387/1-1127 NGHQAEDLSRDDLLFLLSILEGELQARDEVIGILKAEKMDLALLEAQYGFVTPKKVLEAL XP_004858017.1/1-1128 NSYQAEDLSRDDLLFLLSILEGELQARDEVIGILKAEKMDLALLEAQYGFVTPKKVLEAL :.:::*****************************:***:*******:************* ENSMUSP00000124179/1-1131 QRDAFQAKSAPWQEDIYEKPMNELDKVVEKHKESHRRILEQLLMVERSHRQTIMEMEEEK ENSRNOP00000045927/1-1129 QRDAFQVKSAPWQEDIYEKPMNELDKVIEKHKDSDRRIVEQLLMVEKSHRQTIMEMEEEK ENSP00000346560/1-1135 QRDAFQAKSTPWQEDIYEKPMNELDKVVEKHKESYRRILGQLLVAEKSRRQTILELEEEK ENSCPOP00000000387/1-1127 QRDAFQAKSAPWQEDIYEKPMKELDKVVEKHKESHRRLLEQLLMVEKSHRQTILELEKEK XP_004858017.1/1-1128 QRDAFQAKSAPWREDIYEKPMKELDKVVEKYKESHKRILEQLLKVEKSHRQTILELEKEK ******.**:**:********:*****:**:*:* :*:: *** .*:*:****:*:*:** ENSMUSP00000124179/1-1131 RKHKEYMKKSDEFINLLEQECERLKKLIDQETASQEKKEQEKEKRIKTLKEELTKLKSFA ENSRNOP00000045927/1-1129 RKHKEYMERSDEFINLLEQECERLKKLIDQETESQEKKEQEKEKRIKALKEELTKLKSFA ENSP00000346560/1-1135 RKHKEYMEKSDEFICLLEQECERLKKLIDQEIKSQEEKEQEKEKRVTTLKEELTKLKSFA ENSCPOP00000000387/1-1127 IKHKEYMEKSDDFISLLEQECDRLKKLTNQQTESQEK--EQEKKRVIALKEELTKLKSFA XP_004858017.1/1-1128 IKHKEYMEKSDEFISLLEQECERLKKLTDQETESQEKKEQEKEKRVTALKEELTKLKSFA ******::**:** ******:***** :*: ***: ::::**: :************ ENSMUSP00000124179/1-1131 LMVVDEQQRLTAQLALQRQKIQALTTSAKETQGKLALAEARAQEEEQKATRLEKELQTQT ENSRNOP00000045927/1-1129 LMVVDEQQRLTAQLALQRQKIQDLATSAKETQGKLAVAEARAQEEEQKAARLEKELQTQT ENSP00000346560/1-1135 LMVVDEQQRLTAQLTLQRQKIQELTTNAKETHTKLALAEARVQEEEQKATRLEKELQTQT ENSCPOP00000000387/1-1127 LMVVDEQQRLTAQLALQRQKIHDLTTSAKETHAKLALAEARIQEEEQKTSRLKKELQTQT XP_004858017.1/1-1128 LMVVDEQQRLTAQLALQRQKIQDLTTSAKETHAKLALAEARIQEEEQKASRLEKELQTQT **************:******: *:*.****: ***:**** ******::**:******* ENSMUSP00000124179/1-1131 TEFHQNQDKIMAKLTNEDSQNRQLRQKLAALSRQIDELEETNRSLRKAEEELQDIKDKIN ENSRNOP00000045927/1-1129 TEFQQNQDKIMAKLTNEDSQNRQLRQKLAALSRQIDELEETNRSLRKAEEELQDIKEKIN ENSP00000346560/1-1135 TKFHQDQDTIMAKLTNEDSQNRQLQQKLAALSRQIDELEETNRSLRKAEEELQDIKEKIS ENSCPOP00000000387/1-1127 TKFHQSQDEIMAKLTNEDSQNRQLRQKLTALSRQIDELEETNRSLRKAEEELQDIKEKIN XP_004858017.1/1-1128 TKFHQNQDEIMAKLTNEDSQNCQLRQKLAALSRQIDELEETNRSLRKAEEELQDIKEKIN *:*:*.** ************ **:***:***************************:**. ENSMUSP00000124179/1-1131 KGEYGNSGIMDEVDELRKRVLDMEGKDEELIKMEEQCRDLNKRLEKETVQSKDFKLEVDK ENSRNOP00000045927/1-1129 KGEYGDSGIMDEVDELRKRVLDMEGKDEELIKMEEQCRDLNKRLEKETVQSKDFKLEVDK ENSP00000346560/1-1135 KGEYGNAGIMAEVEELRKRVLDMEGKDEELIKMEEQCRDLNKRLERETLQSKDFKLEVEK ENSCPOP00000000387/1-1127 KGEYGNTGILTEVEELRKRVLDMEGKDEELIKMEEQCRDLNKRLEKETTQTKDFKAEVEK XP_004858017.1/1-1128 KGEYGNIGILAEVEELRKRVLDMEGKDEELIKMEEQCRDLNKRLEKETTQSKDFKLEVEK *****: **: **:*******************************:** *:**** **:* ENSMUSP00000124179/1-1131 LSVRITALEKLEDALDKSKQECYSLKCNLEKEKMTTKQLSEELESLNARIKELEAIESRL ENSRNOP00000045927/1-1129 LSIRITALEKLEDALDKSKQECYSLKCNLEKEKMTTKQLSEELESLNARIKELEAIESRL ENSP00000346560/1-1135 LSKRIMALEKLEDAFNKSKQECYSLKCNLEKERMTTKQLSQELESLKVRIKELEAIESRL ENSCPOP00000000387/1-1127 LNKRIMALEKLEDAFNKSKQECYSLKCNLEKEKMTTKQLSQELESLKVRIKELEAIESRL XP_004858017.1/1-1128 LNKRIMALEKLEDAFNKSKQECYSLKCNLEKEKMITKQLSQELESLKVRIKELETIESRL *. ** ********::****************:* *****:*****:.******:***** ENSMUSP00000124179/1-1131 EKTEITLKDDLTKLKTLTVMLVDERKTMSEKLKQTEDKLQSTTSQLQAEQNKVTTVTEKL ENSRNOP00000045927/1-1129 EKTEITLKDDLTKLKTLTVMLVDERKTMSEKLKQTEDKLQTTASQLQAEQNKVTTVTEKL ENSP00000346560/1-1135 EKTEFTLKEDLTKLKTLTVMFVDERKTMSEKLKKTEDKLQAASSQLQVEQNKVTTVTEKL ENSCPOP00000000387/1-1127 EKTEFTLKEDLTKLKTLTVMLVDERKTMSEKLKQTEDKLQAAASQLQVEQNKVTTVTEKL XP_004858017.1/1-1128 EQTEFTLKEDLTKLKTLTVMLVDERKTMNEKLKQTEDKLQAASSQLQVEQNKVTTVTETL *:**:***:***********:*******.****:******:::****.**********.* ENSMUSP00000124179/1-1131 IEETKRALKSKTDAEEKMYSVTKERDDLRNKLKAEEEKGHDLLSKVTILKNRLQSLEAIE ENSRNOP00000045927/1-1129 IEETKRALKSKSDAEEKMYSVTKERDDLRNKLKAEEEKGHDLLSKVTVLKNRLQSLEAIE ENSP00000346560/1-1135 IEETKRALKSKTDVEEKMYSVTKERDDLKNKLKAEEEKGNDLLSRVNMLKNRLQSLEAIE ENSCPOP00000000387/1-1127 IEETKKALKSKTDVEEKMYSVTKERDDLKNKLKAEEEKGNDLLSKVSMLKNRLQSLEPIE XP_004858017.1/1-1128 IEETKRALKSKTDVEEKMYSVTKERDDLKNKLKTEEEKGNDLLSKVSMLKTRLQSLEAIE *****:*****:*.**************:****:*****:****:*.:**.******.** ENSMUSP00000124179/1-1131 KDFVKNKLNQDSSKSTAALHQENNKIKELSQEVENLKLKLKDMKAIEDDLMKTEDEYETL ENSRNOP00000045927/1-1129 KDFVKNKLNQDSSKSTAALHQENNKIKELSQEVEKLKLKLKDMKAIEDDLMKTEDEYETL ENSP00000346560/1-1135 KDFLKNKLNQDSGKSTTALHQENNKIKELSQEVERLKLKLKDMKAIEDDLMKTEDEYETL ENSCPOP00000000387/1-1127 KDFLKNKLNQDSGKSTTALHQENNKIKELSQEVERLKLKLKDMKAIEDDLMKTEDEYETL XP_004858017.1/1-1128 KDFLKNKLNQDSGKSTTALHQENNKIKELSQEVERLKLKLKDMKAIEDDLMKTEDEYETL ***:********.***:*****************.************************* ENSMUSP00000124179/1-1131 ERRYANERDKAQFLSQELEHAKMELAKYKLAEKTESSHEQWLFRRLQEEEAKSGHLSREV ENSRNOP00000045927/1-1129 ERRYANERDKAQFLSQELEHAKMELAKYKLAEKTESSHEQWLFRRLQEEEAKSGHLSREV ENSP00000346560/1-1135 ERRYANERDKAQFLSKELEHVKMELAKYKLAEKTETSHEQWLFKRLQEEEAKSGHLSREV ENSCPOP00000000387/1-1127 ERKYADERDKAQFLSEELEHVKMELAKYKLAEKTESSHEQWLFKRLQEEESKSGHLSREV XP_004858017.1/1-1128 ERRYADERDKAQFLSEELEHVKMELAKYKLAEKTESSHEQWLFKRLQEEEAKSGHLSREV **:**:*********:****.**************:*******:******:********* ENSMUSP00000124179/1-1131 DALKEKIHEYMATEDLICHLQGDHSLLQKKLNQQENRNRDLGREIENLTKELERYRHFSK ENSRNOP00000045927/1-1129 DALKEKIHEYMATEDLICHLQGDHSVLQKKLNQQENRNKDLGREIENLTKELERYRHFSK ENSP00000346560/1-1135 DALKEKIHEYMATEDLICHLQGDHSVLQKKLNQQENRNRDLGREIENLTKELERYRHFSK ENSCPOP00000000387/1-1127 DALKEKIHEYMATEDLIRHLQGDHSVLQKKLNQQENRNRDLGREIENLTKELERYRHFNK XP_004858017.1/1-1128 DTLKEKIHEYMATEDLICHLQGDHSVLQKKLNQQENRNRDLGREIENLNKELERYRHFNK *:*************** *******:************:*********.*********.* ENSMUSP00000124179/1-1131 SLRPSLNERRISDPQVFSKEVQTEAADSEPPDYKSLIPLERAVINGQFYEENEDQDDDPN ENSRNOP00000045927/1-1129 SLRPSPNGRRICDPQVFSKEVQTEAADSEPPDYKSLIPLERPVINGQLYEEKEDQDDDPN ENSP00000346560/1-1135 SLRPSLNGRRISDPQVFSKEVQTEAVDNEPPDYKSLIPLERAVINGQLYEESENQDEDPN ENSCPOP00000000387/1-1127 SLRPSLNGRRISDPQVFSKEVQTEA-DNEPPDYKSLIPLERAVINGQLHEESEDQDEDTN XP_004858017.1/1-1128 SHWPTLNGRRISDPQVFSKEVQTEAVDNEPPDYKSLIPLEQAVINGQLYEESEDQDEDPN * *: * ***.************* *.************:.*****::**.*:**:*.* ENSMUSP00000124179/1-1131 EEE-SVLSFRCSQSSSLPMNRKLWIPWMKSKEGHPQNGKIQTKSNGNFVQPGDLVLSHTP ENSRNOP00000045927/1-1129 EEE-AVLSFRCSPSTSLPMNRKLWIPWMKSKEGHPQNGKIQTRSNGNFVQPGDLVLSHTP ENSP00000346560/1-1135 DEG-SVLSFKCSQSTPCPVNRKLWIPWMKSKEGHLQNGKMQTKPNANFVQPGDLVLSHTP ENSCPOP00000000387/1-1127 EEEDSVLSFKCNPFTPLPGNRKLWIPWMKSKEGHPQNGKIQTKPNGNFVQPGDLVLSHTP XP_004858017.1/1-1128 EE--SVLSFKCNPSGPLPVNRKLWIPWMKSKEGPPQNGKIQTKHNGNFVQPGDLVLSHTP :* :****:*. . * ************** ****:**: *.************** ENSMUSP00000124179/1-1131 GQPLHIKVTPDHIQNTATLEITSPTTESPHSYTSTAVIPNCGTPKQRITILQNASITPIK ENSRNOP00000045927/1-1129 GQPLHIKVTPDHTQNTATLEITSPTTESPHSYTSTAVIPNCGTPKQRITILQNASITPVK ENSP00000346560/1-1135 GQPLHIKVTPDHVQNTATLEITSPTTESPHSYTSTAVIPNCGTPKQRITILQNASITPVK ENSCPOP00000000387/1-1127 GQPLHIKVTPDHVQNTATLEITSPTTESPHCYTSTAVIPNCGTPKQRITILQNASITPMK XP_004858017.1/1-1128 GQPLHIKVTPDHIQNTATLEITSPTTESPHCYTSTAVIPNCGIPKQRITILQNASITPVK ************ *****************.*********** ***************:* ENSMUSP00000124179/1-1131 SKSSTESLMNLEQSMSPVTMATFARAQTPESCGSVTPERTMSPIQVLAMTGSPSSPEQGC ENSRNOP00000045927/1-1129 SKSSTESLMNLEQSMPPVTMATFARAQTPESCGSVTPERTMSPIQVLAMTGSPSSPEQGC ENSP00000346560/1-1135 SKTSTEDLMNLEQGMSPITMATFARAQTPESCGSLTPERTMSPIQVLAVTGSASSPEQGR ENSCPOP00000000387/1-1127 SKTSTEGLMNLDQGMPPITVATFARTQTPESCDSMTPERTMSPIQVLAVTGSPSSPEQGR XP_004858017.1/1-1128 SKTSTEGLMNLEQGVSPITMATFARAQTPESCDSITPERTISPIQVLAVTGSTSSPEQGR **:***.****:*.:.*:*:*****:******.*:*****:*******:***.****** ENSMUSP00000124179/1-1131 SPEPIEISAKHAIFRVSPDRQSSWQFQRSNSNSSSVITTEDNKIHIHLGSPYMQAVAGPM ENSRNOP00000045927/1-1129 SPEPIEISAKHAIFRVSPDRQSSWQFQRSNSNSSSVITTEDNKIHIHLGSPYMQAVAGPV ENSP00000346560/1-1135 SPEPTEISAKHAIFRVSPDRQSSWQFQRSNSNSSSVITTEDNKIHIHLGSPYMQAVASPV ENSCPOP00000000387/1-1127 SPEPIEISAKHAIFRVSPDRQ-SWEFQRSNSNSSSVITTEDNKIHIHLGSPYMQAVASPV XP_004858017.1/1-1128 SPEPIEISAKHAIFRVSPDRQ-SWQFQRSNSNSSSVITTEDNKIHIHLGSPYMQAVASPV **** **************** **:********************************.*: ENSMUSP00000124179/1-1131 RPASPSAPLQDNRTQGLTNGALNKTTNKVTSSITITPTATPLPRQSQITVSNIYN-- ENSRNOP00000045927/1-1129 RPASPS--LQDNRTQGLTNGALNKTTNKVTSSITITPTATPLPRQSQITVSNIYN-- ENSP00000346560/1-1135 RPASPSAPLQDNRTQGLINGALNKTTNKVTSSITITPTATPLPRQSQITVEPLLLPH ENSCPOP00000000387/1-1127 RPGSPPTPLQDNRTQGITHGAQNKTTNKVTSSITITPTGTTLPRQSQITVSNIYN-- XP_004858017.1/1-1128 RPASPSTPLQDNRTQGITNGTLNKTTNKVTSSITITPTATTLPRQSQITVSNIYN-- **.**. ********: :*: ****************.*.*********. :