CLUSTAL W(1.81) multiple sequence alignment ENSCPOP00000000124/1-1249 -KTVQDSISHVF------------------------------------------------ ENSMUSP00000116231/1-1522 MKAVRNLLIYIFSTYLLVMFGFNAAQDFWCSTLVKGVIYGSYSVSEMFPKNFTNCTWTLE ENSRNOP00000016194/1-1522 MKAVRNLLIYIFSTYLLVMFGFNAAQDFWCSTLVKGVIYGSYSVSEMFPKNFTNCTWTLE XP_004846171.1/1-1522 MKAVRNLLIYIFSTYLLVMFGFNAAQDFWCSTLVKGVIYGSYSVSEMFPKNFTNCTWTLE ENSP00000359630/1-1522 MKAVRNLLIYIFSTYLLVMFGFNAAQDFWCSTLVKGVIYGSYSVSEMFPKNFTNCTWTLE *:*:: : ::* ENSCPOP00000000124/1-1249 ------------------------------------------------------------ ENSMUSP00000116231/1-1522 NPDPTKYSIYLKFSKKDLSCSNFSLLAYQFDHFSHEKIKDLLRKNHSIMQLCSSKNAFVF ENSRNOP00000016194/1-1522 NPDPTKYSIYLKFSKKDLSCSNFSLLAYQFDHFSHEKIKDLLRKNHSIMQLCSSKNAFVF XP_004846171.1/1-1522 NPDPTKYSIYLKFSKKDLSCSNFSLLAYQFDHFSHEKIKDLLRKNHSIMQLCNSKNAFVF ENSP00000359630/1-1522 NPDPTKYSIYLKFSKKDLSCSNFSLLAYQFDHFSHEKIKDLLRKNHSIMQLCNSKNAFVF ENSCPOP00000000124/1-1249 ------------------------------------------------------------ ENSMUSP00000116231/1-1522 LQYDKNFIQIRRVFPTDFPGLQKKVEEDQKSFFEFLVLNKVSPSQFGCHVLCTWLESCLK ENSRNOP00000016194/1-1522 LQYDKNFIQIRRVFPSDFPGLQKKGEEDQKSFFEFLVLNKVSPSQFGCHVLCTWLESCLK XP_004846171.1/1-1522 LQYDKNFIQIRRVFPTDFPGLQKKGEEHQKSFFEFLVLNKVSPSQFGCHVLCTWLESCLK ENSP00000359630/1-1522 LQYDKNFIQIRRVFPTNFPGLQKKGEEDQKSFFEFLVLNKVSPSQFGCHVLCTWLESCLK ENSCPOP00000000124/1-1249 -------------------------------------VVL-------------------- ENSMUSP00000116231/1-1522 SENGRTESCGIMYTKCTCPQHLGEWGIDDQSLVLLNNVVLPLNEQTEGCLTQELQTTQVC ENSRNOP00000016194/1-1522 SENGRTESCGVMYTKCTCPQHLGEWGIDDQSLVLLNNVVLPLNEQTEGCLTQELQTTQVC XP_004846171.1/1-1522 SENGRTESCGIMYTKCTCPQHLGEWGIDDQSLVLLNNVVLPLNEQTEGCLTQELQTTQVC ENSP00000359630/1-1522 SENGRTESCGIMYTKCTCPQHLGEWGIDDQSLILLNNVVLPLNEQTEGCLTQELQTTQVC *** ENSCPOP00000000124/1-1249 -----------------------------------------------HAGESGVEEWSQW ENSMUSP00000116231/1-1522 NLTREAKRPPKEEFGMMGDHTIKSQRPRSVHEKRVPQEQADAAKFMAQTGESGVEEWSQW ENSRNOP00000016194/1-1522 NLTREAKRPPKEEFGMMGDHTIKSQRPRSVHEKRVPQEQADAAKFMAQTGESGVEEWSQW XP_004846171.1/1-1522 NLTREARRPPKEEFGMMGDHTIKSQRPRSVHEKKVPQEQADAAKFMAQTGESGVEEWSQW ENSP00000359630/1-1522 NLTREAKRPPKEEFGMMGDHTIKSQRPRSVHEKRVPQEQADAAKFMAQTGESGVEEWSQW ::*********** ENSCPOP00000000124/1-1249 STCSVTCGQGSQVRTRTCVSPYGTHCSGPLRESRVCNNTALCPVHGVWEEWSPWSLCSFT ENSMUSP00000116231/1-1522 SACSVTCGQGSQVRTRTCVSPYGTHCSGPLRESRVCNNTALCPVHGVWEEWSPWSLCSFT ENSRNOP00000016194/1-1522 STCSVTCGQGSQVRTRTCVSPYGTHCSGPLRESRVCNNTALCPVHGVWEEWSPWSLCSFT XP_004846171.1/1-1522 STCSVTCGQGSQVRTRTCVSPYGTHCSGPLRESRVCNNTALCPVHGVWEEWSPWSLCSFT ENSP00000359630/1-1522 STCSVTCGQGSQVRTRTCVSPYGTHCSGPLRESRVCNNTALCPVHGVWEEWSPWSLCSFT *:********************************************************** ENSCPOP00000000124/1-1249 CGRGQRTRTRSCTPPQYGGRPCEGPETHHKPCNIALCPVDGQWQEWSSWSQCSVTCSNGT ENSMUSP00000116231/1-1522 CGRGQRTRTRSCTPPQYGGRPCEGPETHHKPCNIALCPVDGQWQEWSSWSHCSVTCSNGT ENSRNOP00000016194/1-1522 CGRGQRTRTRSCTPPQYGGRPCEGPETHHKPCNIALCPVDGQWQEWSSWSHCSVTCSNGT XP_004846171.1/1-1522 CGRGQRTRTRSCTPPQYGGRPCEGPETHHKPCNIALCPVDGQWQEWSSWSQCSVTCSNGT ENSP00000359630/1-1522 CGRGQRTRTRSCTPPQYGGRPCEGPETHHKPCNIALCPVDGQWQEWSSWSQCSVTCSNGT **************************************************:********* ENSCPOP00000000124/1-1249 QQRSRQCTAAAHGGSECRGPWAESRECYNPECTANGQWNPWGHWSGCSKSCDGGWERRMR ENSMUSP00000116231/1-1522 QQRSRQCTAAAHGGSECRGPWAESRECYNPECTANGQWNQWGHWSGCSKSCDGGWERRMR ENSRNOP00000016194/1-1522 QQRSRQCTAAAHGGSECRGPWAESRECYNSECTANGQWNQWGHWSGCSKSCDGGWERRVR XP_004846171.1/1-1522 QQRSRQCTAAAHGGSECRGPWAESRECYNSECTANGQWNQWGHWSGCSKSCDGGWERRIR ENSP00000359630/1-1522 QQRSRQCTAAAHGGSECRGPWAESRECYNPECTANGQWNQWGHWSGCSKSCDGGWERRIR *****************************.********* ******************:* ENSCPOP00000000124/1-1249 TCQGAAITGQQCEGTGEEVRRCSEQRCPAPYEICPEDYLMSMVWKRTPAGDLAFNQCPLN ENSMUSP00000116231/1-1522 TCQGAAVTGQQCEGTGEEVRRCSEQRCPAPYEICPEDYLISMVWKRTPAGDLAFNQCPLN ENSRNOP00000016194/1-1522 TCQGVTVTGQQCEGTSEEIRRCSEQRCPAPYEICPEDVLISMVWKRTPAGDLAFNQCPLN XP_004846171.1/1-1522 TCQGMAVTGQQCEGTGEEVRRCSEQRCPAPYEICPEDYMMSMVWKRTPAGDLAFNQCPLN ENSP00000359630/1-1522 TCQGAVITGQQCEGTGEEVRRCNEQRCPAPYEICPEDYLMSMVWKRTPAGDLAFNQCPLN **** .:********.**:***.************** ::******************** ENSCPOP00000000124/1-1249 ATGATSRRCSLSLHGVAFWEQPSFARCISNEYRHLQHSIKEHLAKGQRMLAGDGMSQVTK ENSMUSP00000116231/1-1522 ATGTTSRRCSLSLHGVASWEQPSFARCISNEYRHLQHSIKEHLAKGQRMLAGDGMSQVTK ENSRNOP00000016194/1-1522 ATGTTSRRCSLSLHGVASWEQPSFARCISNEYRHLQHSIKEHLAKGQRMLAGDGMSQVTK XP_004846171.1/1-1522 ATGTTSRRCSLSLHGVAFWEQPSFARCISNEYRHLQHSIKEHLAKGQRMLAGDGMSQVTK ENSP00000359630/1-1522 ATGTTSRRCSLSLHGVAFWEQPSFARCISNEYRHLQHSIKEHLAKGQRMLAGDGMSQVTK ***:************* ****************************************** ENSCPOP00000000124/1-1249 TLLDLTQRKNFYAGDLLMSVEILRNVTDTFKRASYIPASDGVQNFFQIVSNLLDEENKEK ENSMUSP00000116231/1-1522 TLLDLTQRKNFYAGDLLVSVEILRNVTDTFKRASYIPASDGVQNFFQIVSNLLDEENKEK ENSRNOP00000016194/1-1522 TLLDLTQRKNFYAGDLLVSVEILRNVTDTFKRASYIPASDGVQNFFQIVSNLLDEENKEK XP_004846171.1/1-1522 TLLDLTQRKNFYAGDLLMSVEILRNVTDTFKRASYIPASDGVQNFFQIVSNLLDEENKEK ENSP00000359630/1-1522 TLLDLTQRKNFYAGDLLMSVEILRNVTDTFKRASYIPASDGVQNFFQIVSNLLDEENKEK *****************:****************************************** ENSCPOP00000000124/1-1249 WEDAQQIYPGSIELMQVIEDFIHIVGMGMMDFQNSYLMTGNVVASIQKLPAASVLTDINF ENSMUSP00000116231/1-1522 WEDAQQIYPGSIELMQVIEDFIHIVGMGMMDFQNSYLMTGNVVASIQKLPAASVLTDINF ENSRNOP00000016194/1-1522 WEDAQQIYPGSIELMQVIEDFIHIVGMGMMDFQNSYLMTGNVVASIQKLPAASVLTDINF XP_004846171.1/1-1522 WEDAQQIYPGSIELMQVIEDFIHIVGMGMMDFQNSYLMTGNVVASIQKLPAASVLTDINF ENSP00000359630/1-1522 WEDAQQIYPGSIELMQVIEDFIHIVGMGMMDFQNSYLMTGNVVASIQKLPAASVLTDINF ************************************************************ ENSCPOP00000000124/1-1249 PMKGRKGMVDWARNSEDRVVIPKSIFTPVSSKELDESSVFVLGAVLYKNLDLILPTLRNY ENSMUSP00000116231/1-1522 PMKGRKGMVDWARNSEDRVVIPKSIFTPVSSKELDESSVFVLGAVLYKNLDLILPTLRNY ENSRNOP00000016194/1-1522 PMKGRKGMVDWARNSEDRVVIPKSIFTPVSSKELDESSVFVLGAVLYKNLDLILPTLRNY XP_004846171.1/1-1522 PMKGRKGMVDWARNSEDRVVIPKSIFTPVSSKELDESSVFVLGAVLYKNLDLILPTLRNY ENSP00000359630/1-1522 PMKGRKGMVDWARNSEDRVVIPKSIFTPVSSKELDESSVFVLGAVLYKNLDLILPTLRNY ************************************************************ ENSCPOP00000000124/1-1249 TVVNSKIIVVTIRPEPKTTDSFLEIELAHLANGTLNPYCVLWDDSKMNESLGAWSTQGCK ENSMUSP00000116231/1-1522 TVVNSKVIVVTIRPEPKTTDSFLEIELAHLANGTLNPYCVLWDDSKSNESLGTWSTQGCK ENSRNOP00000016194/1-1522 TVVNSKIIVVTIRPEPKRTDAFLEIELAHLANGTLNPYCVLWDDSKSNESLGTWSTQGCK XP_004846171.1/1-1522 TVVNSKIIVVTIRPEPKTTDSFLEIELAHLANGTFNPYCVLWDDSKTNESLGTWSTQGCK ENSP00000359630/1-1522 TVINSKIIVVTIRPEPKTTDSFLEIELAHLANGTLNPYCVLWDDSKTNESLGTWSTQGCK **:***:********** **:*************:*********** *****:******* ENSCPOP00000000124/1-1249 TVLTDASHTKCLCDRLSTFAILAQQPREIIMESSGTPSVTLIVGSGLSCLALITLAVVYA ENSMUSP00000116231/1-1522 TVLTDASHTKCLCDRLSTFAILAQQPREIVMESSGTPSVTLIVGSGLSCLALITLAVVYA ENSRNOP00000016194/1-1522 TVLTDASHTKCLCDRLSTFAILAQQPREIVMESSGTPSVTLIVGSGLSCLALITLAVVYA XP_004846171.1/1-1522 TVLTDASHTKCLCDRLSTFAILAQQPREIIMESSGTPSVTLIVGSGLSCLALITLAVVYA ENSP00000359630/1-1522 TVLTDASHTKCLCDRLSTFAILAQQPREIIMESSGTPSVTLIVGSGLSCLALITLAVVYA *****************************:****************************** ENSCPOP00000000124/1-1249 ALWRYIRSERSIILINFCLSIISSNILILVGQTQTHNKSICTTTTACLHFFFLASFCWVL ENSMUSP00000116231/1-1522 ALWRYIRSERSIILINFCLSIISSNILILVGQTQTHNKSICTTTTAFLHFFFLASFCWVL ENSRNOP00000016194/1-1522 ALWRYIRSERSIILINFCLSIISSNILILVGQTQTHNKSICTTTTAFLHFFFLASFCWVL XP_004846171.1/1-1522 ALWRYIRSERSIILINFCLSIISSNILILVGQTQTHNKSICTTTTACLHFFFLASFCWVL ENSP00000359630/1-1522 ALWRYIRSERSIILINFCLSIISSNILILVGQTQTHNKSICTTTTAFLHFFFLASFCWVL ********************************************** ************* ENSCPOP00000000124/1-1249 TEAWQSYMAVTGKIRTRLIRKRFLCLGWGLPALVVATSVGFTRTKGYGTDHYCWLSLEGG ENSMUSP00000116231/1-1522 TEAWQSYMAVTGKIRTRLIRKRFLCLGWGLPALVVATSVGFTRTKGYGTDHYCWLSLEGG ENSRNOP00000016194/1-1522 TEAWQSYMAVTGKIRTRLIRKRFLCLGWGLPALVVATSVGFTRTKGYGTDHYCWLSLEGG XP_004846171.1/1-1522 TEAWQSYMAVTGKIRTRLIRKRFLCLGWGLPALVVATSVGFTRTKGYGTDHYCWLSLEGG ENSP00000359630/1-1522 TEAWQSYMAVTGKIRTRLIRKRFLCLGWGLPALVVATSVGFTRTKGYGTDHYCWLSLEGG ************************************************************ ENSCPOP00000000124/1-1249 LLYAFVGPAAAVVLVNMVIGILVFNKLVSRDGILDKKLKHRAGQMSEPHSGLTLKCAKCG ENSMUSP00000116231/1-1522 LLYAFVGPAAAVVLVNMVIGILVFNKLVSRDGILDKKLKHRAGQMSEPHSGLTLKCAKCG ENSRNOP00000016194/1-1522 LLYAFVGPAAAVVLVNMVIGILVFNKLVSRDGILDKKLKHRAGQMSEPHSGLTLKCAKCG XP_004846171.1/1-1522 LLYAFVGPAAAVVLVNMVIGILVFNKLVSRDGILDKKLKHRAGQMSEPHSGLTLKCAKCG ENSP00000359630/1-1522 LLYAFVGPAAAVVLVNMVIGILVFNKLVSRDGILDKKLKHRAGQMSEPHSGLTLKCAKCG ************************************************************ ENSCPOP00000000124/1-1249 VVSTTALSATTASNAMASLWSSCVVLPLLALTWMSAVLAMTDKRSILFQILFAVFDSLQG ENSMUSP00000116231/1-1522 VVSTTALSATTASNAMASLWSSCVVLPLLALTWMSAVLAMTDKRSILFQILFAVFDSLQG ENSRNOP00000016194/1-1522 VVSTTALSAATASNAMASLWSSCVVLPLLALTWMSAVLAMTDKRSILFQILFAVFDSLQG XP_004846171.1/1-1522 VVSTTALSATTASNAMASLWSSCVVLPLLALTWMSAVLAMTDKRSILFQILFAVFDSLQG ENSP00000359630/1-1522 VVSTTALSATTASNAMASLWSSCVVLPLLALTWMSAVLAMTDKRSILFQILFAVFDSLQG *********:************************************************** ENSCPOP00000000124/1-1249 FVIVMVHCILRREVQDAFRCRLRNCQDPINADSSSSFPNGHAQIMTDFEKDVDIACRSVL ENSMUSP00000116231/1-1522 FVIVMVHCILRREVQDAFRCRLRNCQDPINADSSSSFPNGHAQIMTDFEKDVDIACRSVL ENSRNOP00000016194/1-1522 FVIVMVHCILRREVQDAFRCRLRNCQDPINADSSSSFPNGHAQIMTDFEKDVDIACRSVL XP_004846171.1/1-1522 FVIVMVHCILRREVQDAFRCRLRNCQDPINADSSSSFPNGHAQIMTDFEKDVDIACRSVL ENSP00000359630/1-1522 FVIVMVHCILRREVQDAFRCRLRNCQDPINADSSSSFPNGHAQIMTDFEKDVDIACRSVL ************************************************************ ENSCPOP00000000124/1-1249 HKDIGPCRAATITGTLSRISLNDDEEEKGTSPEGLSYSTLPGNVISKVIIQQPTGLHMPM ENSMUSP00000116231/1-1522 HKDIGPCRAATITGTLSRISLNDDEEEKGTNPEGLSYSTLPGNVISKVIIQQPTGLHMPM ENSRNOP00000016194/1-1522 HKDIGPCRAATITGTLSRISLNDEEEEKGTNPEGLSYSTLPGNVISKVIIQQPTALHMPM XP_004846171.1/1-1522 HKDIGPCRAATITGTLSRISLNDDEEEKGANPEGLSYSTLPGNVISKVIIQQPTGLHMPM ENSP00000359630/1-1522 HKDIGPCRAATITGTLSRISLNDDEEEKGTNPEGLSYSTLPGNVISKVIIQQPTGLHMPM ***********************:*****:.***********************.***** ENSCPOP00000000124/1-1249 SMNELSSQCLKKENSELRRTVYLCTEDNLRGADIDIVHPQERMMESDYIVMPRSSVNTQP ENSMUSP00000116231/1-1522 SMNELSNPCLKKENTELRRTVYLCTDDNLRGADMDIVHPQERMMESDYIVMPRSSVSTQP ENSRNOP00000016194/1-1522 SMNELSNPCLKKENTELRRTVYLCTDDNLRGADMDIVHPQERMMESDYIVMPRSSVSTQP XP_004846171.1/1-1522 SMNELSSQCLKKENSELRRTVYLCTDDSLRGADMDIVHPQERMMESDYIVMPRSSVNTQP ENSP00000359630/1-1522 SMNELSNPCLKKENSELRRTVYLCTDDNLRGADMDIVHPQERMMESDYIVMPRSSVNNQP ******. ******:**********:*.*****:**********************..** ENSCPOP00000000124/1-1249 SLKEESKMNIGMETLPHERLLHYKVNPEFNMNPPVMDQFNMNLDQHLAPQEHMQNLPFEP ENSMUSP00000116231/1-1522 SMKEESKMNIGMETLPHERLLHYKVNPEFNMNPPVMDQFNMNLDQHLAPQEHMQNLPFEP ENSRNOP00000016194/1-1522 SMKEESKMNIGMETLPHERLLHYKVNPEFNMNPPVMDQFNMNLDQHLAPQEHMQNLPFEP XP_004846171.1/1-1522 SLKEESKMNIGMETLPHERLLHYKVNPEFNMNPPVMDQFNMNLEQHLAPQEHIQNLPFEP ENSP00000359630/1-1522 SMKEESKMNIGMETLPHERLLHYKVNPEFNMNPPVMDQFNMNLEQHLAPQEHMQNLPFEP *:*****************************************:********:******* ENSCPOP00000000124/1-1249 RTAVKNFMATELDDNAGLSRSETGSTISMSSLERRKSRYSDLDFEKVMHTRKRHMELFQE ENSMUSP00000116231/1-1522 RTAVKNFMASELDDNVGLSRSETGSTISMSSLERRKSRYSDLDFEKVMHTRKRHMELFQE ENSRNOP00000016194/1-1522 RTAVKNFMASELDDNAGLSRSETGSTISMSSLERRKSRYSDLDFEKVMHTRKRHMELFQE XP_004846171.1/1-1522 RTAVKNFMAAELDDNAGLSRSETGSTISMSSLERRKSRYSDLDFEKVMHTRKRHMELFQE ENSP00000359630/1-1522 RTAVKNFMASELDDNAGLSRSETGSTISMSSLERRKSRYSDLDFEKVMHTRKRHMELFQE *********:*****.******************************************** ENSCPOP00000000124/1-1249 LNQKFQTLDRFRDIPNTSSMENPTPNKNPWDTFKAPSEYQHYTTINVLDTEAKDALELRP ENSMUSP00000116231/1-1522 LNQKFQTLDRFRDIPNTSSMENPAPNKNPWDTFKPPSEYQHYTTINVLDTEAKDTLELRP ENSRNOP00000016194/1-1522 LNQKFQTLDRFRDIPNTSSMENPAPNKNPWDTFKTPSEYPHYTTINVLDTEAKDALELRP XP_004846171.1/1-1522 LNQKFQTLDRFRDIPNTSSMENPAPNKNPWDTFKTPSEYQHYTTINVLDTEAKDALELRP ENSP00000359630/1-1522 LNQKFQTLDRFRDIPNTSSMENPAPNKNPWDTFKNPSEYPHYTTINVLDTEAKDALELRP ***********************:********** **** **************:***** ENSCPOP00000000124/1-1249 AEWEKCLNLPLDVQEGDFQTEV ENSMUSP00000116231/1-1522 AEWEKCLNLPLDVQEGDFQTEV ENSRNOP00000016194/1-1522 AEWEKCLNLPLDVQEGDFQTEV XP_004846171.1/1-1522 AEWEKCLNLPLDVQEGDFQTEV ENSP00000359630/1-1522 AEWEKCLNLPLDVQEGDFQTEV **********************