CLUSTAL W(1.81) multiple sequence alignment ENSP00000315351/1-521 ----------------------MLPRRPLAWPAWLLRGAPG---AAGSWGRPVG------ ENSMUSP00000108502/1-557 MRMLCACRVVFFRLSPLSRAGTMVLPLVSRWSARVLWASPGWRRT-YTQRACVG-LKRLG ENSRNOP00000025711/1-527 ----------------------MVLHLVPRWSASLFRASPRWKKT-YSQRASAQ-LKWLG ENSCPOP00000000006/1-538 ----------------------MVLHQMLRWSVWIFRASPGWWRTTYTFGASVGQQRWPS XP_004868564.1/1-538 ----------------------MVSHQVPRWSAWIFRASPGWQRTACAPGASVGQQRWPR *: *.. :: .:* : : . ENSP00000315351/1-521 -------PLARRGCCS-APGTPEVPLTRERYPVRRLPFSTVSKQDLAAFERIVPGGVVTD ENSMUSP00000108502/1-557 CPRGVYSPLAHR-AYSVVAGGPEVTLTPERYPVQRLPFSTVSEEDLAAFECIIPGRVITD ENSRNOP00000025711/1-527 CPRSVYSPLACR-AYSKVSGSPEVMLTPERYPVQRLPFSTVSEEDLAAFECIIPGRVITD ENSCPOP00000000006/1-538 FAWVMSSPLAFRSSYSTVPHIPSVMLTSERYSVQRLPFSMVSEEDLASFECIIPGRVITD XP_004868564.1/1-538 IPWQVSGPLAFRGCASTAPRVPRVMPTSERYPVQRLPFSVVSEEDLAAFERIIPGRVITD *** * . * .. * * * ***.*:***** **::***:** *:** *:** ENSP00000315351/1-521 PEALQAPNVDWLRTLRGCSKVLLRPRTSEEVSHILRHCHERNLAVNPQGGNTGMVGGSVP ENSMUSP00000108502/1-557 PEQLQTCNVDWLKTVRGCSKVLLRPQTSEEVSQILRHCYKRNLAVNPQGGNTGMVGGSVP ENSRNOP00000025711/1-527 PEQLQTCNVDWLRTVRGCSKVLLRPQTSEEVSQILRHCYKRNLAVNPQGGNTGMVGGSVP ENSCPOP00000000006/1-538 PEELEVANVDWLRSVRGCSKVLLKPRTTEEVSCILRHCHQRNLAVNPQGGNTGLVGGSVP XP_004868564.1/1-538 PEELEVANVDWLRTVRGCSKVLLRPRTTEEVSHILRHCHQRNLAVNPQGGNTGMVGGSVP ** *:. *****:::********:*:*:**** *****::*************:****** ENSP00000315351/1-521 VFDEIILSTARMNRVLSFHSVSGILVCQAGCVLEELSRYVEERDFIMPLDLGAKGSCHIG ENSMUSP00000108502/1-557 VFDEVILSTALMNQVISFHDVSGILVCQAGCVLEELSRYVQERDFIMPLDLGAKGSCHIG ENSRNOP00000025711/1-527 VFDEVILSTALMNQVISFHDVSGILVCQAGCVLEELSRYVQERDFIMPLDLGAKGSCHIG ENSCPOP00000000006/1-538 VFDEIILSTALMNQVISFHDVSGILVCQAGCVLEELNHYVQDRGFIMPLDLGAKGSCHIG XP_004868564.1/1-538 VFDEIILSTALMNQVISFHDVSGILVCQAGCVLEELNHYVQERGFIMPLDLGAKGSCHIG ****:***** **:*:***.****************.:**::*.**************** ENSP00000315351/1-521 GNVATNAGGLRFLRYGSLHGTVLGLEVVLADGTVLDCLTSLRKDNTGYDLKQLFIGSEGT ENSMUSP00000108502/1-557 GNVATNAGGLRFLRYGSLRGTVLGLEVVLADGTILNCLTSLRKDNTGYDLKQMFIGSEGT ENSRNOP00000025711/1-527 GNVATNAGGLRFLRYGSLRGTVLGLEVVLADGTILNCLTSLRKDNTGYDLKQMFIGSEGT ENSCPOP00000000006/1-538 GNVATNAGGVRFLRYGSLRGTVLGLEVVLADGTVLDCLTSLRKDNTGYDLKQLFIGSEGT XP_004868564.1/1-538 GNVATNAGGLRFLRYGSLRGTVLGLEVVLADGTVLDCLTSLRKDNTGYDLKQLFIGSEGT *********:********:**************:*:****************:******* ENSP00000315351/1-521 LGIITTVSILCPPKPRAVNVAFLGCPGFAEVLQTFSTCKGMLGEILSAFEFMDAVCMQLV ENSMUSP00000108502/1-557 LGVITAVSIVCPPRPKAVNVAFLGCPGFAEVLQTFRTCRGMLGEILSAFEFMDTECMQLV ENSRNOP00000025711/1-527 LGVITAVSIVCPPRPKAVNVAFLGCPGFTEVLQTFRTCKGQLGEILSAFEFMDAECMQLV ENSCPOP00000000006/1-538 LGVITAVSILCPPRPKAVNVAFLGCPGFAEVLQVFSTCKGMLGEILSAFEFMDAECMQLV XP_004868564.1/1-538 LGVITAVSISCPPRPKAVNVAFLGCPGFAEVLQAFSTCKGTLGEILSAFEFMDAECMQLV **:**:*** ***:*:************:****.* **:* ************: ***** ENSP00000315351/1-521 GRHLHLASPVQESPFYVLIETSGSNAGHDAEKLGHFLEHALGSGLVTDGTMATDQRKVKM ENSMUSP00000108502/1-557 GQHLQLTNPVQESPFYVLVETSGSSAGHDAEKLTNVLEQVLNSGLVTDGTMATDQRKVQM ENSRNOP00000025711/1-527 GQHLHLTNPVQESPFYVLVETSGSSAGHDAEKLTNVLEQVLNSGLVIDGTMATDQRKVQM ENSCPOP00000000006/1-538 GQHLHLTRPVRESPFYVLVETSGSSADHDMEKLDGFLEQALGSGLVTDGTVGTDQSKVQA XP_004868564.1/1-538 GQHLHLARPVRESPFYILVETSGSSAEHDAEKLDGFLEQALGSGLVTDGTVGTDQSKAQS *:**:*: **:*****:*:*****.* ** *** .**:.*.**** ***:.*** *.: ENSP00000315351/1-521 LWALRERITEALSRDGYVYKYDLSLPVERLYDIVTDLRARLGPHAKHVVGYGHLGDGNLH ENSMUSP00000108502/1-557 LWALRERITEALSRDGYVFKYDLSLPVERLYDLVIDLRTRLGPRAKHVVGYGHLGDGNLH ENSRNOP00000025711/1-527 LWALRERITEALSRDGYVFKYDLSLPVERLYDLVIDLRTRLGPRAKHVVGYGHLGDGNLH ENSCPOP00000000006/1-538 LWALRERITEALSHDGYVFKYDVSIPVERFYDLVTDLRTRLGPRVKHVVGYGHLGDGNLH XP_004868564.1/1-538 LWALRERITEALSHDGYVFKYDVSLPVERFYDLVSDLRARLGPRAKHVVGYGHLGDGNLH *************:****:***:*:****:**:* ***:****:.*************** ENSP00000315351/1-521 LNVTAEAFSPSLLAALEPHVYEWTAGQQGSVSAEHGVGFRKRDVLGYSKPPGALQLMQQL ENSMUSP00000108502/1-557 LNVTAEAFSRELLGALEPYVYAWTAEQRGSVSAEHGLGFKKKDVLGYSKPPVAVTLMQQL ENSRNOP00000025711/1-527 LNVTAEAFSQELLGALEPYVYAWTAEQRGSVSAEHGLGFKKKNVLGYSATCGC------- ENSCPOP00000000006/1-538 LNVTAEAFSASLLAALEPYVYTWTAAQQGSVSAEHGLGFKKKDVLGYSKTPAAVQLMWQL XP_004868564.1/1-538 LNVTAEAFSTALLGALEPYVYTWTAAQRGSVSAEHGLGLRKKDVLGYSKPPTAVQLMWQL ********* **.****:** *** *:********:*::*::***** . . ENSP00000315351/1-521 KALLDPKGILNPYKTLPSQA ENSMUSP00000108502/1-557 KAMLDPEGILNPYKTLPAQA ENSRNOP00000025711/1-527 EAYATAEGHAGPQRH-PEPL ENSCPOP00000000006/1-538 KALLDPRGLLNPYKTLPAHL XP_004868564.1/1-538 KALLDPRGLLNPYKTLPAHA :* ..* .* : *